The chemical understanding of biomolecular recognition in epigenetics

Publikacje

Recognition of Dimethylarginine Analogues by Tandem Tudor Domain Protein Spindlin1

Autorzy: Miriam R. B. Porzberg, Laust Moesgaard, Catrine Johansson, Udo Oppermann, Jacob Kongsted, Jasmin Mecinović
Opublikowane w: Molecules, Numer 27, 2022, Strona(/y) 983, ISSN 1420-3049
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/molecules27030983

Targeting SARS-CoV-2 spike protein by stapled hACE2 peptides

Autorzy: Marijn N. Maas, Jordi C. J. Hintzen, Philipp M. G. Löffler, Jasmin Mecinović
Opublikowane w: Chemical Communications, Numer 57/26, 2021, Strona(/y) 3283-3286, ISSN 1364-548X
Wydawca: Royal Society of Chemistry
DOI: 10.1039/d0cc08387a

Trimethyllysine: From Carnitine Biosynthesis to Epigenetics

Autorzy: Marijn N. Maas, Jordi C. J. Hintzen, Miriam R. B. Porzberg, Jasmin Mecinović
Opublikowane w: International Journal of Molecular Sciences, Numer 21/24, 2020, Strona(/y) 9451, ISSN 1422-0067
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms21249451

Effect of lysine side chain length on histone lysine acetyltransferase catalysis

Autorzy: Giordano Proietti, Yali Wang, Giorgio Rainone, Jasmin Mecinović
Opublikowane w: Scientific Reports, Numer 10/1, 2020, Strona(/y) 13046, ISSN 2045-2322
Wydawca: Nature Publishing Group
DOI: 10.1038/s41598-020-69510-0

Exploring the Histone Acylome through Incorporation of γ-Thialysine on Histone Tails

Autorzy: Giordano Proietti, Giorgio Rainone, Jordi C. J. Hintzen, Jasmin Mecinović
Opublikowane w: Bioconjugate Chemistry, Numer 31/3, 2020, Strona(/y) 844-851, ISSN 1043-1802
Wydawca: American Chemical Society
DOI: 10.1021/acs.bioconjchem.0c00012

Substrate Scope for Human Histone Lysine Acetyltransferase KAT8

Autorzy: Giordano Proietti, Yali Wang, Chiara Punzo, Jasmin Mecinović
Opublikowane w: International Journal of Molecular Sciences, Numer 22/2, 2021, Strona(/y) 846, ISSN 1422-0067
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22020846

Recognition of shorter and longer trimethyllysine analogues by epigenetic reader proteins

Autorzy: Abbas H. K. Al Temimi, Roman Belle, Kiran Kumar, Jordi Poater, Peter Betlem, Bas J. G. E. Pieters, Robert S. Paton, F. Matthias Bickelhaupt, Jasmin Mecinović
Opublikowane w: Chemical Communications, Numer 54/19, 2018, Strona(/y) 2409-2412, ISSN 1359-7345
Wydawca: Royal Society of Chemistry
DOI: 10.1039/c8cc01009a

Investigating d -lysine stereochemistry for epigenetic methylation, demethylation and recognition

Autorzy: Roman Belle, Abbas H. K. Al Temimi, Kiran Kumar, Bas J. G. E. Pieters, Anthony Tumber, James E. Dunford, Catrine Johansson, Udo Oppermann, Tom Brown, Christopher J. Schofield, Richard J. Hopkinson, Robert S. Paton, Akane Kawamura, Jasmin Mecinović
Opublikowane w: Chemical Communications, Numer 53/99, 2017, Strona(/y) 13264-13267, ISSN 1359-7345
Wydawca: Royal Society of Chemistry
DOI: 10.1039/c7cc08028j

Installation of Trimethyllysine Analogs on Intact Histones via Cysteine Alkylation

Autorzy: Bas J. G. E. Pieters, Jordi C. J. Hintzen, Yvonne Grobben, Abbas H. K. Al Temimi, Jos J. A. G. Kamps, Jasmin Mecinović
Opublikowane w: Bioconjugate Chemistry, Numer 30/3, 2019, Strona(/y) 952-958, ISSN 1043-1802
Wydawca: American Chemical Society
DOI: 10.1021/acs.bioconjchem.9b00065

The nucleophilic amino group of lysine is central for histone lysine methyltransferase catalysis

Autorzy: Abbas H. K. Al Temimi, Helene I. V. Amatdjais-Groenen, Y. Vijayendar Reddy, Richard H. Blaauw, Hong Guo, Ping Qian, Jasmin Mecinović
Opublikowane w: Communications Chemistry, Numer 2/1, 2019, Strona(/y) 112, ISSN 2399-3669
Wydawca: Nature Publishing Group
DOI: 10.1038/s42004-019-0210-8

γ-Thialysine versus Lysine: An Insight into the Epigenetic Methylation of Histones

Autorzy: Abbas H. K. Al Temimi, Renate van der Wekken-de Bruijne, Giordano Proietti, Hong Guo, Ping Qian, Jasmin Mecinović
Opublikowane w: Bioconjugate Chemistry, Numer 30/6, 2019, Strona(/y) 1798-1804, ISSN 1043-1802
Wydawca: American Chemical Society
DOI: 10.1021/acs.bioconjchem.9b00313

Methylation of geometrically constrained lysine analogues by histone lysine methyltransferases

Autorzy: Abbas H. K. Al Temimi, Paul B. White, Marcus J. M. Mulders, Nicole G. A. van der Linden, Richard H. Blaauw, Anita Wegert, Floris P. J. T. Rutjes, Jasmin Mecinović
Opublikowane w: Chemical Communications, Numer 56/20, 2020, Strona(/y) 3039-3042, ISSN 1359-7345
Wydawca: Royal Society of Chemistry
DOI: 10.1039/c9cc09098c

Examining sterically demanding lysine analogs for histone lysine methyltransferase catalysis

Autorzy: Abbas H. K. Al Temimi, Vu Tran, Ruben S. Teeuwen, Arthur J. Altunc, Helene I. V. Amatdjais-Groenen, Paul B. White, Danny C. Lenstra, Giordano Proietti, Yali Wang, Anita Wegert, Richard H. Blaauw, Ping Qian, Wansheng Ren, Hong Guo, Jasmin Mecinović
Opublikowane w: Scientific Reports, Numer 10/1, 2020, ISSN 2045-2322
Wydawca: Nature Publishing Group
DOI: 10.1038/s41598-020-60337-3

Comparison of Molecular Recognition of Trimethyllysine and Trimethylthialysine by Epigenetic Reader Proteins

Autorzy: Jordi C. J. Hintzen, Jordi Poater, Kiran Kumar, Abbas H. K. Al Temimi, Bas J. G. E. Pieters, Robert S. Paton, F. Matthias Bickelhaupt, Jasmin Mecinović
Opublikowane w: Molecules, Numer 25/8, 2020, Strona(/y) 1918, ISSN 1420-3049
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/molecules25081918

Mechanism of biomolecular recognition of trimethyllysine by the fluorinated aromatic cage of KDM5A PHD3 finger

Autorzy: Bas J. G. E. Pieters, Maud H. M. Wuts, Jordi Poater, Kiran Kumar, Paul B. White, Jos J. A. G. Kamps, Woody Sherman, Ger J. M. Pruijn, Robert S. Paton, Thijs Beuming, F. Matthias Bickelhaupt, Jasmin Mecinović
Opublikowane w: Communications Chemistry, Numer 3/1, 2020, Strona(/y) 69, ISSN 2399-3669
Wydawca: Nature Publishing Group
DOI: 10.1038/s42004-020-0313-2

Fine-tuning of lysine side chain modulates the activity of histone lysine methyltransferases

Autorzy: Abbas H. K. Al Temimi, Jona Merx, Christian J. van Noortwijk, Giordano Proietti, Romano Buijs, Paul B. White, Floris P. J. T. Rutjes, Thomas J. Boltje, Jasmin Mecinović
Opublikowane w: Scientific Reports, Numer 10/1, 2020, Strona(/y) 21574, ISSN 2045-2322
Wydawca: Nature Publishing Group
DOI: 10.1038/s41598-020-78331-0

Reading and erasing of the phosphonium analogue of trimethyllysine by epigenetic proteins

Autorzy: Roman Belle, Jos J. A. G. Kamps, Jordi Poater, Kiran Kumar, Bas J. G. E. Pieters, Eidarus Salah, Timothy D. W. Claridge, Robert S. Paton, F. Matthias Bickelhaupt, Akane Kawamura, Christopher J. Schofield, Jasmin Mecinović
Opublikowane w: Communications Chemistry, Numer 5, 2022, Strona(/y) 27, ISSN 2399-3669
Wydawca: Nature Publishing Group
DOI: 10.1038/s42004-022-00640-4

Biomolecular Recognition of Methylated Histones

Autorzy: Miriam R. B. Porzberg, Bas J. G. E. Pieters, Jasmin Mecinović
Opublikowane w: The DNA, RNA, and Histone Methylomes, 2019, Strona(/y) 435-451, ISBN 978-3-030-14791-4
Wydawca: Springer International Publishing
DOI: 10.1007/978-3-030-14792-1_17

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