Risultati finali Documents, reports (41) Lifespan-applicable versus age-specific risk and protective factors Analysis to distinguish which risk and protective factors work when Lifebrain conference in Oxford Organization and completion of conference Lifebrain gender equity report (R) The management in coordination with the Safety Board (SB) team will ensure and monitor that the consortium’s policy regarding gender issues is correctly implemented, including the awareness and sensitisation programmes. Communication management routines and infrastructure implemented Establish routines for communication amongst consortium partners including the exchange of information and materials, while ensuring maintenance the EC Grant Agreement and Consortium Agreement. Provide assistance and advice to partners regarding administrative matters, and to ensure compliance with EC rules including the communication with and reporting to the EC on behalf of the consortium Multi-modal MRI-data processing stream which allows for a state-of-the art central integration of data across sites A standardized analysis stream will be developed that all data can be run through, with special focus put on neuroimaging. Enrichment of existing cohorts by home collection of DBS to be analysed across WP4 tasks 2-6 Kits for home collection of DBS will be sent to participants in all samples, which will send them back to Vitas for analyses, with the aim of getting 2000 samples Lifebrain conference in Berlin Organization and completion of conference Risk and protective factors for cognitive and mental health in broader epidemiological samples Divided into two parts: A) Using multivariate regression analysis and multilevel/hierarchical models, existing European Research Infrastructure Consortia (ERICs, SHARE) will be leveraged to analyze i) how cognitive performance and risks of depression and anxiety differ by socioeconomic status (SES), gender and age, ii) how these patterns differ across regions/countries, and iii) the extent to which the cognitive outcomes are associated with differences in health and everyday functioning. B) Based on results from task A, population-covering administrative register data from Scandinavian countries will be used to corroborate the real-world relevance of these findings Business plan/s for post-project exploitation opportunities Will examine the results achieved in the project and how this can lead to the uptake of productsservices to the market place As a minimum a business plan will be delivered for the exploitation of the advanced VITAS DBS Home kits and how this will be launched into the market place postproject and for use in LCBC and other multidisciplinary research investigations Online/mobile tools for stakeholder engagement conceptualized and developed Prepare tools and platform for stakeholder engagement. Social media, like twitter, will be one area of interest. Also web-based questionnaires, tests and engagement tools will be considered, and possibly developed Tool for post hoc harmonization of MRI data across sites, to allow integration of data from different scanners/sites Implement and test a novel procedure to correct images for scanner-specific differences in tissue contrast and intensity non-uniformity. Refining and validation of novel statistical tools Tool refinement and optimizing the model selection ie to tackle the important problem of identifying and selecting those models that best summarize data across sites Reviewing Stakeholders Engagement - Best Practice Presentation of comprehensive review of the stakeholder engagement in the project and production of a Best Practice report Enrichment of existing cohorts by administration of buccal swabs for epigenetic analyses across WP4 tasks 2-6 Coordination of the sample collection, laboratory experiments and bioinformatic processing of the data for analysis in WP4 Input to the Dissemination, Exploitation and Communication(DEC) plan (T5.1) Prepare tools and platform for stakeholder engagement, ensure that WP1 is fully aligned with WP5s DEC plan DBS assays for relevant biomarkers for data enrichment Develop and validate new additional biomarkers on DBS tailored for the Lifebrain project Input from Stakeholders – Feedback Incorporated Innovative approaches to retrieve stakeholder’s input and feedback will be developed and implemented. Timeline will be drawn and meeting arenas will be identified for the various phases and stakeholders, including relevant existing conferences and workshops where a stakeholder symposium might be added DEC Strategy, Operative Plan and SOPs for the Lifebrain project Details the communication and dissemination strategy including stakeholder engagement practices for targeting different audiences and resulting in the definition of a detailed activity plan for phase one (M1-30). The operative part of the DEC Plan will be updated based on project activities and experiences. Standard operating procedures (SOPs) for publications, participation in conferences and exploitation will be annexed to this plan Data storage and processing system to share data, manage data access and integrated analysis Establish an international image sharing, storage and processing platform for management of neuroimaging and harmonized target variables Online platform for collection of questionnaire and test data for data enrichment The implementation will include three major steps: (a) identifying and operationalizing (e.g., selecting standard and custom questionnaires, or neuropsychological tests) the variables to be assessed; (b) translating the instructions, questionnaires/test items or identifying language-specific version for standard questionnaires/tests); (c) implementing a OS independent internet browser-based platform which allows for data collection and transfer of data using secure file transfer protocol. Policy reviews to advance well-being across all age groups - II Selected NationalEuropean policies will be reviewed and policymakers engaged to determine the appropriateness and relevance of project results and how these results can lead to promotion of policies on personalised health opportunities for European citizens Exploitation and IP management strategy - I An integrated IP and exploitation strategy will be defined and implemented along with innovative communication channels developed List of relevant stakeholders for project engagement Identify and invite research participant groups, patient groups, clinicians and policy makers that will have an interest in the project and that should be taken into consideration Individual pathways and mediator variables in relation to risk for poor cognitive function and decline versus resilience Analysis in the integrated project cohort to identify whether individual differences in relation to risk for poor cognitive function and decline versus resilience are mediated by variations in lifestyle body mass index blood pressure cholesterol and other blood markers vitamins fatty acids proteins genetics epigenetics and brain factors Individual pathways and mediator variables in relation to risk for mental health problems and resilience Analyses in the integrated project cohort are to identify whether individual differences in mental health and resilience are mediated via variations in lifestyle smoking alcohol drugs body mass index blood pressure cholesterol and other blood markers vitamins fatty acid protein status metals genetic epigenetic factors and brain structure and function Enrichment of existing cohorts by online data collection Develop and apply a tool for online collection of data to enrich available database, allowing Lifebrain databases to attain data which not all sites have available and data on new variables, and by doing so optimize the utilization of the existing data DEC strategy and Operative plan – Update Update strategy report conducted under D5.1 Financial and legal management routines implemented To establish a robust management structure to ensure that the objectives of the project are met within agreed budget and timeframe, granting that the administrative, legal and ethical aspects are fulfilled by each partner and ensuring that allocated finances are appropriately managed and reported, carrying out adequate quality control of the work performed and of the deliverables; Data harmonization guidelines and standardized data management/processing protocol across sites We will develop and implement harmonization protocols, i.e. develop technical and semantic data standards, and quality protocols to unify and bridge the different coding standards of target variables between sites Exploitation and IP management strategy - Updated An IP management strategy will be delivered considering the necessary and most appropriate consortium agreement to lead to effective exploitation opportunities postproject This will also examine the results achieved in the project and how this can lead to the uptake of productsservices to the market place Report/policy brief on concepts and mechanisms for uptake of research output Specific focus on engagement with policy makers and identification of the mechanisms that will enable uptake of research outputs. GWAS data and harmonization of genetic data across samples for genetic analyses across WP4 tasks 2-6 This will include re-calling of genotypes, from existing genome-wide SNP genotype data, quality checking, imputation, determination of population substructure, and producing of analysis-ready genotypes maximally harmonized across the different Lifebrain centres. Replication, validation and extension of findings in non-European samples Part of the analyses from T4246 will be redone in US databases PING ADNI NACC VETSA RUSH to replicate and extend findings identify differences and crossvalidate statistical models Novel longitudinal statistical tools, allowing to tackle challenges associated with multi-side mixed model lifespan data Develop tools where goal is to identify models that optimally represent the consolidated findings of the consortium, and hence contribute to theory development and generalizability. Gender-specific risk and protective factors Analyses to identify sexspecific differences in developmental trajectories of brain and behavioral measures and how these are related to life style factors eg physical activity and substances use and bodily functions eg hormones and metabolic profiles Moderating effects of genetic epigenetic factors and biological markers will be investigated Societal factors mitigating genetic/ epigenetic risk for neurodegenerative disease and their mediators We will test whether the effects of SES differ across societies applying the Nordic model Denmark REGIONH Norway UiO Sweden UMU and the Netherlands VUMC the Continental model Germany MPIB the British model UK UOXF UCAM and the Mediterranean model Spain UB Simultaneously frequency of risk alleles for developing Alzheimers disease APOE 4 differs across Europe with higher risk allele frequency in Northern Europe Dissemination tools and communication strategies - I Tools include both printed material (flyers, flyer inlays, posters and factsheets etc.) as well as online / digital tools - website, social media accounts, newsletters and power point presentations. Project partners will be actively involved in determining appropriate tools, content generation and dissemination & communication opportunities associated with agreed DEC activities. Kick-off meeting completed; advisory board, safety board, executive board instantiated Organization of meeting and establishment of relevant boards Dissemination tools and communication strategies II Update strategy report conducted under D5.2 Data obtained from national registries; incl standardization, integration, quality control and pooling with existing data across sites Coupling of existing data with national health, conscription and population registries. This will be done for the Nordic countries (Norway, Sweden, Denmark) as well as the Netherlands and Spain. Policy reviews on cognitive & mental well-being across all age groups - I Selected National/European policies will be reviewed and policy-makers engaged to determine the appropriateness and relevance of project results and how these results can lead to promotion of policies on ‘personalised health’ opportunities for European citizens Pubblicazioni Other (5) How to promote citizens’ brain health? Insights from the Global Brain HealthSurvey on citizen’s perceptions of brain health interventions Autori: Lifebrain consortium Pubblicato in: 2022, ISBN 978-82-8406-223-5 Editore: Lifebrain consortium Nettskjema R-package Autori: Athanasia Monika Mowinckel, Waldir Leoncio Pubblicato in: Open Access R-package at Zenodo, 2021 Editore: University of Oslo DOI: 10.5281/zenodo.4745481 Associations between abdominal adipose tissue, reproductive span, and brain characteristics in post-menopausal women Autori: Schindler LS., Subramaniapillai S., Barth C., van der Meer D., Pedersen ML., Kaufmann T., Maximov II., Linge J., Leinhard OD., Beck D., Gurholt TP., Voldsbekk I., SURI S., EBMEIER KP., Draganski B., Andreassen OA., Westlye LT., de Lange A-MG. (2022) Pubblicato in: OSF preprint, 2022 Editore: Center for Open Science DOI: 10.31219/osf.io/vr9uz What motivates people to look after their brain health? Insights from the Global Brain Health Survey. Autori: Lifebrain consortium Pubblicato in: 2022, ISBN 978-82-8406-267-9 Editore: Lifebrain consortium Global Brain Health Survey raw data Autori: Budin-Ljøsne I, Friedman BB, Suri S, Solé-Padullés C, Düzel S, Drevon CA, Baaré WFC, Mowinckel AM, Zsoldos E, Madsen KS, Carver RB, Ghisletta P, Arnesen MR, Bartrés Faz D, Brandmaier AM, Fjell AM, Kvalbein A, Henson RN, Kievit RA, Nawijn L, Pochet R, Schnitzler A, Walhovd KB and Zasiekina L Pubblicato in: 2022 Editore: Lifebrain consortium Peer reviewed articles (63) Education and Income Show Heterogeneous Relationships to Lifespan Brain and Cognitive Differences Across European and US Cohorts Autori: Kristine B Walhovd, Anders M Fjell, Yunpeng Wang, Inge K Amlien, Athanasia M Mowinckel, Ulman Lindenberger, Sandra Düzel, David Bartrés-Faz, Klaus P Ebmeier, Christian A Drevon, William F C Baaré, Paolo Ghisletta, Louise Baruël Johansen, Rogier A Kievit, Richard N Henson, Kathrine Skak Madsen, Lars Nyberg, Jennifer R Harris, Cristina Solé-Padullés, Sara Pudas, Øystein Sørensen, René Weste Pubblicato in: Cerebral Cortex, 2021, ISSN 1047-3211 Editore: Oxford University Press DOI: 10.1093/cercor/bhab248 TEMPORARY REMOVAL: Hippocampal maintenance after a 12-month physical activity intervention in older adults: The REACT MRI study Autori: Naiara Demnitz, Afroditi Stathi, Janet Withall, Candida Stainer, Poppy Seager, Jolanthe De Koning, Patrick Esser, Thomas Wassenaar, Helen Dawes, Jonathan Brooks, Klaus P. Ebmeier, Heidi Johansen-Berg, Claire E. Sexton Pubblicato in: NeuroImage: Clinical, 2021, Pagina/e 102762, ISSN 2213-1582 Editore: Elsevier BV DOI: 10.1016/j.nicl.2021.102762 Associations of dietary markers with brain volume and connectivity: A systematic review of MRI studies Autori: Daria E.A. Jensen, Virginia Leoni, Miriam C. Klein-Flügge, Klaus P. Ebmeier, Sana Suri Pubblicato in: Ageing Research Reviews, Numero 70, 2021, Pagina/e 101360, ISSN 1568-1637 Editore: Elsevier BV DOI: 10.1016/j.arr.2021.101360 Prediction of brain age and cognitive age: Quantifying brain and cognitive maintenance in aging Autori: Melis Anatürk, Tobias Kaufmann, James H. Cole, Sana Suri, Ludovica Griffanti, Enikő Zsoldos, Nicola Filippini, Archana Singh‐Manoux, Mika Kivimäki, Lars T. Westlye, Klaus P. Ebmeier, Ann‐Marie G. de Lange Pubblicato in: Human Brain Mapping, 2020, ISSN 1065-9471 Editore: John Wiley & Sons Inc. DOI: 10.1002/hbm.25316 Associations between depression, lifestyle and brain structure: A longitudinal MRI study Autori: Julia Binnewies, Laura Nawijn, Marie-José van Tol, Nic J.A. van der Wee, Dick J. Veltman, Brenda W.J.H. Penninx Pubblicato in: NeuroImage, Numero 231, 2021, Pagina/e 117834, ISSN 1053-8119 Editore: Academic Press DOI: 10.1016/j.neuroimage.2021.117834 Individual variations in ‘brain age’ relate to early-life factors more than to longitudinal brain change Autori: Didac Vidal-Pineiro, Yunpeng Wang, Stine K Krogsrud, Inge K Amlien, William FC Baaré, David Bartres-Faz, Lars Bertram, Andreas M Brandmaier, Christian A Drevon, Sandra Düzel, Klaus Ebmeier, Richard N Henson, Carme Junqué, Rogier Andrew Kievit, Simone Kühn, Esten Leonardsen, Ulman Lindenberger, Kathrine S Madsen, Fredrik Magnussen, Athanasia Monika Mowinckel, Lars Nyberg, James M Roe, Barbara S Pubblicato in: eLife, Numero 10, 2021, ISSN 2050-084X Editore: eLife Sciences Publications DOI: 10.7554/elife.69995 Associations between arterial stiffening and brain structure, perfusion, and cognition in the Whitehall II Imaging Sub-study: A retrospective cohort study. Autori: Sana Suri; Scott T Chiesa; Enikő Zsoldos; Clare E. Mackay; Nicola Filippini; Ludovica Griffanti; Abda Mahmood; Archana Singh-Manoux; Archana Singh-Manoux; Martin J. Shipley; Eric J. Brunner; Mika Kivimäki; John E. Deanfield; Klaus P. Ebmeier Pubblicato in: PLoS Medicine, Vol 17, Iss 12, p e1003467 (2020), Numero 15491676, 2020, ISSN 1549-1676 Editore: PLOS DOI: 10.1371/journal.pmed.1003467 Successful Memory Aging Autori: Lars Nyberg, Sara Pudas Pubblicato in: Annual Review of Psychology, Numero 70/1, 2019, Pagina/e 219-243, ISSN 0066-4308 Editore: Annual Reviews, Inc. DOI: 10.1146/annurev-psych-010418-103052 Poor Self-Reported Sleep is Related to Regional Cortical Thinning in Aging but not Memory Decline—Results From the Lifebrain Consortium Autori: Anders M Fjell, Øystein Sørensen, Inge K Amlien, David Bartrés-Faz, Andreas M Brandmaier, Nikolaus Buchmann, Ilja Demuth, Christian A Drevon, Sandra Düzel, Klaus P Ebmeier, Paolo Ghisletta, Ane-Victoria Idland, Tim C Kietzmann, Rogier A Kievit, Simone Kühn, Ulman Lindenberger, Fredrik Magnussen, Didac Macià, Athanasia M Mowinckel, Lars Nyberg, Claire E Sexton, Cristina Solé-Padullés, Sara Pubblicato in: Cerebral Cortex, Numero 31/4, 2020, Pagina/e 1953-1969, ISSN 1047-3211 Editore: Oxford University Press DOI: 10.1093/cercor/bhaa332 tDCS-Induced Memory Reconsolidation Effects and Its Associations With Structural and Functional MRI Substrates in Subjective Cognitive Decline Autori: Lídia Vaqué-Alcázar, Lídia Mulet-Pons, Kilian Abellaneda-Pérez, Cristina Solé-Padullés, María Cabello-Toscano, Dídac Macià, Roser Sala-Llonch, Nuria Bargalló, Javier Solana, Gabriele Cattaneo, José M. Tormos, Alvaro Pascual-Leone, David Bartrés-Faz Pubblicato in: Frontiers in Aging Neuroscience, Numero 13, 2021, ISSN 1663-4365 Editore: Frontiers Research Foundation DOI: 10.3389/fnagi.2021.695232 Integrating large-scale neuroimaging research datasets: Harmonisation of white matter hyperintensity measurements across Whitehall and UK Biobank datasets Autori: Valentina Bordin, Ilaria Bertani, Irene Mattioli, Vaanathi Sundaresan, Paul McCarthy, Sana Suri, Enikő Zsoldos, Nicola Filippini, Abda Mahmood, Luca Melazzini, Maria Marcella Laganà, Giovanna Zamboni, Archana Singh-Manoux, Mika Kivimäki, Klaus P Ebmeier, Giuseppe Baselli, Mark Jenkinson, Clare E Mackay, Eugene P Duff, Ludovica Griffanti Pubblicato in: NeuroImage, Numero 237, 2021, Pagina/e 118189, ISSN 1053-8119 Editore: Academic Press DOI: 10.1016/j.neuroimage.2021.118189 Alcohol consumption and MRI markers of brain structure and function: Cohort study of 25,378 UK Biobank participants Autori: Anya Topiwala; Klaus P. Ebmeier; Thomas Maullin-Sapey; Thomas E. Nichols Pubblicato in: NeuroImage: Clinical, Numero 22131582, 2022, Pagina/e 103066, ISSN 2213-1582 Editore: Elsevier BV DOI: 10.1016/j.nicl.2022.103066 No Association Between Loneliness, Episodic Memory and Hippocampal Volume Change in Young and Healthy Older Adults: A Longitudinal European Multicenter Study Autori: Solé-Padullés Cristina, Macià Dídac, Andersson Micael, Stiernstedt Mikael, Pudas Sara, Düzel Sandra, Zsoldos Enikő, Ebmeier Klaus P., Binnewies Julia, Drevon Christian A., Brandmaier Andreas M., Mowinckel Athanasia M., Fjell Anders M., Madsen Kathrine Skak, Baaré William F. C., Lindenberger Ulman, Nyberg Lars, Walhovd Kristine B., Bartrés-Faz David Pubblicato in: Neurocognitive Ageing and Behaviour, 2022, ISSN 1663-4365 Editore: Frontiers Research Foundation DOI: 10.3389/fnagi.2022.795764 Brain aging differs with cognitive ability regardless of education Autori: Walhovd, K.B., Nyberg, L., Lindenberger, U. et al. Pubblicato in: Scientific Reports, Numero 20452322, 2022, Pagina/e 13886, ISSN 2045-2322 Editore: Nature Publishing Group DOI: 10.1038/s41598-022-17727-6 Greater lifestyle engagement is associated with better age-adjusted cognitive abilities Autori: G. Sophia Borgeest, Richard N. Henson, Meredith Shafto, David Samu, Rogier A. Kievit Pubblicato in: PLOS ONE, Numero 15/5, 2020, Pagina/e e0230077, ISSN 1932-6203 Editore: Public Library of Science DOI: 10.1371/journal.pone.0230077 Separating vascular and neuronal effects of age on fMRI BOLD signals Autori: Kamen A. Tsvetanov, Richard N. A. Henson, James B. Rowe Pubblicato in: Philosophical Transactions of the Royal Society B: Biological Sciences, Numero 376/1815, 2021, Pagina/e 20190631, ISSN 0962-8436 Editore: Royal Society of London DOI: 10.1098/rstb.2019.0631 Multimodal brain-age prediction and cardiovascular risk: The Whitehall II MRI sub-study Autori: Ann-Marie G. de Lange, Melis Anatürk, Sana Suri, Tobias Kaufmann, James H. Cole, Ludovica Griffanti, Enikő Zsoldos, Daria E.A. Jensen, Nicola Filippini, Archana Singh-Manoux, Mika Kivimäki, Lars T. Westlye, Klaus P. Ebmeier Pubblicato in: NeuroImage, Numero 222, 2020, Pagina/e 117292, ISSN 1053-8119 Editore: Academic Press DOI: 10.1016/j.neuroimage.2020.117292 Longitudinal association between hippocampus atrophy and episodic‐memory decline in non‐demented APOE ε4 carriers Autori: Tetiana Gorbach Sara Pudas David Bartrés‐Faz Andreas M. Brandmaier Sandra Düzel Richard N. Henson Ane‐Victoria Idland Ulman Lindenberger Didac Macià Bros Athanasia M. Mowinckel Cristina Solé‐Padullés Øystein Sørensen Kristine B. Walhovd Leiv Otto Watne René Westerhausen Anders M. Fjell Lars Nyberg Pubblicato in: Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, Numero Volume12, Numero1, 2020, ISSN 2352-8729 Editore: Alzheimer’s Association DOI: 10.1002/dad2.12110 Meta-analysis of generalized additive models in neuroimaging studies Autori: Øystein Sørensen, Andreas M. Brandmaier, Dídac Macià, Klaus Ebmeier, Paolo Ghisletta, Rogier A. Kievit, Athanasia M. Mowinckel, Kristine B. Walhovd, Rene Westerhausen, Anders Fjell Pubblicato in: NeuroImage, Numero 224, 2021, Pagina/e 117416, ISSN 1053-8119 Editore: Academic Press DOI: 10.1016/j.neuroimage.2020.117416 Functional brain changes associated with cognitive trajectories determine specific tDCS‐induced effects among older adults Autori: Lídia Vaqué‐Alcázar, Kilian Abellaneda‐Pérez, Cristina Solé‐Padullés, Núria Bargalló, Cinta Valls‐Pedret, Emilio Ros, Roser Sala‐Llonch, David Bartrés‐Faz Pubblicato in: Journal of Neuroscience Research, Numero 99/9, 2021, Pagina/e 2188-2200, ISSN 0360-4012 Editore: John Wiley & Sons Inc. DOI: 10.1002/jnr.24849 The effects of age on resting‐state BOLD signal variability is explained by cardiovascular and cerebrovascular factors Autori: Kamen A. Tsvetanov, Richard N. A. Henson, P. Simon Jones, Henk Mutsaerts, Delia Fuhrmann, Lorraine K. Tyler, James B. Rowe Pubblicato in: Psychophysiology, Numero 58/7, 2021, ISSN 0048-5772 Editore: Blackwell Publishing Inc. DOI: 10.1111/psyp.13714 Contributing factors to advanced brain aging in depression and anxiety disorders Autori: Laura K. M. Han, Hugo G. Schnack, Rachel M. Brouwer, Dick J. Veltman, Nic J. A. van der Wee, Marie-José van Tol, Moji Aghajani, Brenda W. J. H. Penninx Pubblicato in: Translational Psychiatry, Numero 11/1, 2021, ISSN 2158-3188 Editore: Nature Publishing Group DOI: 10.1038/s41398-021-01524-2 Educational attainment does not influence brain aging Autori: Lars Nyberg, Fredrik Magnussen, Anders Lundquist, William Baaré, David Bartrés-Faz, Lars Bertram, C. J. Boraxbekk, Andreas M. Brandmaier, Christian A. Drevon, Klaus Ebmeier, Paolo Ghisletta, Richard N. Henson, Carme Junqué, Rogier Kievit, Maike Kleemeyer, Ethan Knights, Simone Kühn, Ulman Lindenberger, Brenda W. J. H. Penninx, Sara Pudas, Øystein Sørensen, Lídia Vaqué-Alcázar, Kristine B. Pubblicato in: Proceedings of the National Academy of Sciences, Numero 118/18, 2021, Pagina/e e2101644118, ISSN 0027-8424 Editore: National Academy of Sciences DOI: 10.1073/pnas.2101644118 Study Protocol: The Heart and Brain Study Autori: Sana Suri, Daniel Bulte, Scott T. Chiesa, Klaus P. Ebmeier, Peter Jezzard, Sebastian W. Rieger, Jemma E. Pitt, Ludovica Griffanti, Thomas W. Okell, Martin Craig, Michael A. Chappell, Nicholas P. Blockley, Mika Kivimäki, Archana Singh-Manoux, Ashraf W. Khir, Alun D. Hughes, John E. Deanfield, Daria E. A. Jensen, Sebastian F. Green, Veronika Sigutova, Michelle G. Jansen, Enikő Zsoldos, Clare E. Ma Pubblicato in: Frontiers in Physiology, Numero 12, 2021, ISSN 1664-042X Editore: Frontiers Research Foundation DOI: 10.3389/fphys.2021.643725 The genetic organization of longitudinal subcortical volumetric change is stable throughout the lifespan Autori: Anders M. Fjell; Anders M. Fjell; Håkon Grydeland; Yunpeng Wang; Inge K Amlien; David Bartrés-Faz; Andreas M. Brandmaier; Sandra Düzel; Jeremy A. Elman; Carol E. Franz; Asta Håberg; Tim C. Kietzmann; Rogier A. Kievit; William S. Kremen; William S. Kremen; Stine K. Krogsrud; Simone Kühn; Ulman Lindenberger; Dídac Macià; Athanasia M. Mowinckel; Lars Nyberg; Lars Nyberg; Matthew S. Panizzon; C Pubblicato in: eLife, Numero 2050084X, 2021, ISSN 2050-084X Editore: eLife Sciences Publications DOI: 10.7554/elife.66466 an international, online cross-sectional survey Autori: Isabelle Budin-Ljøsne; Athanasia Monika Mowinckel; Barbara Bodorkos Friedman; Klaus P Ebmeier; Christian A Drevon; Rebecca Bruu Carver; Enikő Zsoldos; Nanna Alida Grit Fredheim; Øystein Sørensen; William Frans Christiaan Baaré; Kathrine Skak Madsen; Anders M Fjell; Rogier A Kievit; Paolo Ghisletta; David Bartrés-Faz; Laura Nawijn; Cristina Solé-Padullés; Kristine B Walhovd; Sandra Düzel; Pubblicato in: VOLUME=12;ISSN=2044-6055;TITLE=BMJ Open, Numero 36, 2022, ISSN 2044-6055 Editore: BMJ Publishing Group DOI: 10.1136/bmjopen-2021-057999 Supplementary materials [Code] to: A tutorial for joint modeling of longitudinal and time to-event data in R. Autori: Cekic, Sezen Aichele, Stephen Brandmaier, Andreas M. Köhncke, Ylva Ghisletta, Paolo Pubblicato in: Quantitative and Computational Methods in Behavioral Sciences, Numero 1(1), e2979, 2021, ISSN 2699-8432 Editore: PsychOpen DOI: 10.23668/psycharchives.4621 Hippocampal and Parahippocampal Gray Matter Structural Integrity Assessed by Multimodal Imaging Is Associated with Episodic Memory in Old Age Autori: Ylva Köhncke, Sandra Düzel, Myriam C Sander, Ulman Lindenberger, Simone Kühn, Andreas M Brandmaier Pubblicato in: Cerebral Cortex, Numero 31/3, 2020, Pagina/e 1464-1477, ISSN 1047-3211 Editore: Oxford University Press DOI: 10.1093/cercor/bhaa287 Effect of apolipoprotein E polymorphism on cognition and brain in the Cambridge Centre for Ageing and Neuroscience cohort Autori: Richard N. Henson, Sana Suri, Ethan Knights, James B. Rowe, Rogier A. Kievit, Donald M. Lyall, Dennis Chan, Else Eising, Simon E. Fisher Pubblicato in: Brain and Neuroscience Advances, Numero 4, 2020, Pagina/e 239821282096170, ISSN 2398-2128 Editore: Sage Journals DOI: 10.1177/2398212820961704 Association of trajectories of depressive symptoms with vascular risk, cognitive function and adverse brain outcomes: The Whitehall II MRI sub-study Autori: NaiaraDemnitz, MelisAnatürk, Charlotte L.Allanc, Nicola Filippini, Ludovica Griffant, Clare E. Mackay , Abda Mahmood, Claire E. Sexton, Sana Suri, Anya G.Topiwala, Enikő Zsoldo, Mika Kivimäk, Archana Singh-Manoux, Klaus P. Ebmeier Pubblicato in: Journal of Psychiatric Research, Numero Volume 131, December 2020, 2020, Pagina/e 85-93, ISSN 0022-3956 Editore: Pergamon Press Ltd. DOI: 10.1016/j.jpsychires.2020.09.005 Forecasting memory function in aging: pattern-completion ability and hippocampal activity relate to visuospatial functioning over 25 years Autori: Lars Nyberg, Xenia Grande, Micael Andersson, David Berron, Anders Lundquist, Mikael Stiernstedt, Anders Fjell, Kristine Walhovd, Greger Orädd Pubblicato in: Neurobiology of Aging, Numero 94, 2020, Pagina/e 217-226, ISSN 0197-4580 Editore: Elsevier BV DOI: 10.1016/j.neurobiolaging.2020.06.005 The Global Brain Health Survey: Development of a Multi-Language Survey of Public Views on Brain Health Autori: Isabelle Budin-Ljøsne, Barbara Bodorkos Friedman, Sana Suri, Cristina Solé-Padullés, Sandra Düzel, Christian A. Drevon, William F. C. Baaré, Athanasia Monika Mowinckel, Enikő Zsoldos, Kathrine Skak Madsen, Rebecca Bruu Carver, Paolo Ghisletta, Mari R. Arnesen, David Bartrés Faz, Andreas M. Brandmaier, Anders Martin Fjell, Aud Kvalbein, Richard N. Henson, Rogier A. Kievit, Laura Nawijn, Rola Pubblicato in: Frontiers in Public Health, Numero 8, 2020, ISSN 2296-2565 Editore: Frontiers in Public Health DOI: 10.3389/fpubh.2020.00387 A common polymorphism in the dopamine transporter gene predicts working memory performance and in vivo dopamine integrity in aging Autori: Nina Karalija, Ylva Köhncke, Sandra Düzel, Lars Bertram, Goran Papenberg, Ilja Demuth, Christina M. Lill, Jarkko Johansson, Katrine Riklund, Martin Lövdén, Lars Bäckman, Lars Nyberg, Ulman Lindenberger, Andreas M. Brandmaier Pubblicato in: NeuroImage, Numero 245, 2021, Pagina/e 118707, ISSN 1053-8119 Editore: Academic Press DOI: 10.1016/j.neuroimage.2021.118707 White matter hyperintensities classified according to intensity and spatial location reveal specific associations with cognitive performance Autori: Luca Melazzini, Clare E Mackay, Valentina Bordin, Sana Suri, Eniko Zsoldos, Nicola Filippini, Abda Mahmood, Vaanathi Sundaresan, Marina Codari, Eugene Duff, Archana Singh-Manoux, Mika Kivimäki, Klaus P Ebmeier, Mark Jenkinson, Francesco Sardanelli, Ludovica Griffanti Pubblicato in: NeuroImage: Clinical, 2021, Pagina/e 102616, ISSN 2213-1582 Editore: Elsevier BV DOI: 10.1016/j.nicl.2021.102616 Healthy minds 0–100 years: Optimising the use of European brain imaging cohorts (“Lifebrain”) Autori: Kristine B. Walhovd, Anders M. Fjell, René Westerhausen, Lars Nyberg, Klaus P. Ebmeier, Ulman Lindenberger, David Bartrés-Faz, William F.C. Baaré, Hartwig R. Siebner, Richard Henson, Christian A. Drevon, Gun Peggy Strømstad Knudsen, Isabelle Budin Ljøsne, Brenda W.J.H. Penninx, Paolo Ghisletta, Ole Rogeberg, Lorraine Tyler, Lars Bertram Pubblicato in: European Psychiatry, Numero 50, 2018, Pagina/e 47-56, ISSN 0924-9338 Editore: Elsevier Masson DOI: 10.1016/j.eurpsy.2017.12.006 Assessing reliability in neuroimaging research through intra-class effect decomposition (ICED) Autori: Andreas M Brandmaier , Elisabeth Wenger, Nils C Bodammer, Simone Kühn, Naftali Raz, Ulman Lindenberger Pubblicato in: eLife, Numero eLife 2018;7:e35718, 2018, ISSN 2050-084X Editore: eLife Sciences Publications DOI: 10.7554/eLife.35718.001 A systematic review and meta-analysis of structural magnetic resonance imaging studies investigating cognitive and social activity levels in older adults Autori: M. Anatürk, N. Demnitz, K.P. Ebmeier, C.E. Sexton Pubblicato in: Neuroscience & Biobehavioral Reviews, Numero 93, 2018, Pagina/e 71-84, ISSN 0149-7634 Editore: Pergamon Press Ltd. 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Henson Pubblicato in: Neurobiology of Aging, Numero 70, 2018, Pagina/e 180-183, ISSN 0197-4580 Editore: Elsevier BV DOI: 10.1016/j.neurobiolaging.2018.06.012 Age Differentiation within Gray Matter, White Matter, and between Memory and White Matter in an Adult Life Span Cohort Autori: Susanne M.M. de Mooij, Richard N.A. Henson, Lourens J. Waldorp, Rogier A. Kievit Pubblicato in: The Journal of Neuroscience, Numero 38/25, 2018, Pagina/e 5826-5836, ISSN 0270-6474 Editore: Society for Neuroscience DOI: 10.1523/jneurosci.1627-17.2018 Strong and specific associations between cardiovascular risk factors and white matter micro- and macrostructure in healthy aging Autori: Delia Fuhrmann, David Nesbitt, Meredith Shafto, James B. Rowe, Darren Price, Andrew Gadie, Rogier A. Kievit, Lorraine K. Tyler, Carol Brayne, Edward T. Bullmore, Andrew C. Calder, Rhodri Cusack, Tim Dalgleish, John Duncan, Richard N. Henson, Fiona E. Matthews, William D. Marslen-Wilson, James B. Rowe, Meredith A. 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Okell, Eniko Zsoldos, Archana Singh-Manoux, Mika Kivimäki, Clare E. Mackay, Klaus P. Ebmeier Pubblicato in: JAMA Network Open, Numero 2/6, 2019, Pagina/e e195776, ISSN 2574-3805 Editore: Jama Network Open DOI: 10.1001/jamanetworkopen.2019.5776 A Practical Guide to Variable Selection in Structural Equation Modeling by Using Regularized Multiple-Indicators, Multiple-Causes Models Autori: Ross Jacobucci, Andreas M. Brandmaier, Rogier A. Kievit Pubblicato in: Advances in Methods and Practices in Psychological Science, Numero 2/1, 2019, Pagina/e 55-76, ISSN 2515-2459 Editore: Sage journals DOI: 10.1177/2515245919826527 Are People Ready for Personalized Brain Health? 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Brandmaier, Paolo Ghisletta, Timo von Oertzen Pubblicato in: Behavior Research Methods, 2020, ISSN 1554-3528 Editore: Springer Publishing DOI: 10.3758/s13428-019-01325-y Association of midlife stroke risk with structural brain integrity and memory performance at older ages: a longitudinal cohort study Autori: Enikő Zsoldos, Abda Mahmood, Nicola Filippini, Sana Suri, Verena Heise, Ludovica Griffanti, Clare E Mackay, Archana Singh-Manoux, Mika Kivimäki, Klaus P Ebmeier Pubblicato in: Brain Communications, Numero 2/1, 2020, ISSN 2632-1297 Editore: Oxford University Press DOI: 10.1093/braincomms/fcaa026 Time, frequency, and time-varying Granger-causality measures in neuroscience Autori: Sezen Cekic, Didier Grandjean, Olivier Renaud Pubblicato in: Statistics in Medicine, Numero 37/11, 2018, Pagina/e 1910-1931, ISSN 0277-6715 Editore: John Wiley & Sons Inc. 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Roe, Mengyu Pan, Fredrik Magnussen, Inge K. Amlien, Leiv Otto Watne, Ane-Victoria Idland, Lars Bertram, Thomas E. Gundersen, Alvaro Pascual-Leone, Maria Cabello-Toscano, Jose M. Tormos, David Bartres-Faz, Christian A. Drevon, Anders M. Fjell, Kristine W. Walhovd Pubblicato in: Brain, Behavior, and Immunity, Numero Volume 100, 2022, Pagina/e 243-253, ISSN 0889-1591 Editore: Academic Press DOI: 10.1016/j.bbi.2021.12.008 Cognition-Mortality Associations Are More Pronounced When Estimated Jointly in Longitudinal and Time-to-Event Models Autori: Aichele, S., Cekic, S., Rabbitt, P., & Ghisletta, P. Pubblicato in: Frontiers in Psychology, 2021, ISSN 1664-1078 Editore: Frontiers Research Foundation DOI: 10.3389/fpsyg.2021.708361 Associations of depression and regional brain structure across the adult lifespan: Pooled analyses of six population-based and two clinical cohort studies in the European Lifebrain consortium Autori: Julia Binnewies, Laura Nawijn, Andreas M. Brandmaier, William F.C. 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Autori: Carver RB, Fredheim NAG, Mowinckel AM, Ebmeier KP, Friedman BB, Rosness TA, Drevon CA, Suri S, Baaré WFC, Zsoldos E, Solé-Padullés C, Bartrés-Faz D, Ghisletta P, Nawijn L, Düzel S, Madsen KS, Fjell AM, Lindenberger U, Walhovd KB and Budin-Ljøsne I Pubblicato in: Frontiers in Public Health, Numero 22962565, 2022, ISSN 2296-2565 Editore: Frontiers Media DOI: 10.3389/fpubh.2022.998302 Age-related reduction in motor adaptation: brain structural correlates and the role of explicit memory Autori: Noham Wolpe, James N. Ingram, Kamen A. Tsvetanov, Richard N. Henson, Daniel M. Wolpert, James B. Rowe, Lorraine K. Tyler, Carol Brayne, Edward T. Bullmore, Andrew C. Calder, Rhodri Cusack, Tim Dalgleish, John Duncan, Fiona E. Matthews, William D. Marslen-Wilson, Meredith A. Shafto, Karen Campbell, Teresa Cheung, Simon Davis, Linda Geerligs, Rogier Kievit, Anna McCarrey, Abdur Mustafa, Darren Price Pubblicato in: Neurobiology of Aging, Numero 90, 2020, Pagina/e 13-23, ISSN 0197-4580 Editore: Elsevier BV DOI: 10.1016/j.neurobiolaging.2020.02.016 The Use of a Hidden Mixture Transition Distribution Model in Clustering Few but Long Continuous Sequences: An Illustration with Cognitive Skills Data Autori: Zhivko Taushanov, Paolo Ghisletta Pubblicato in: Symmetry, Numero 12/10, 2020, Pagina/e 1618, ISSN 2073-8994 Editore: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/sym12101618 Exploratory factor analysis with structured residuals for brain network data Autori: Erik-Jan van Kesteren, Rogier A. Kievit Pubblicato in: Network Neuroscience, Numero 5/1, 2021, Pagina/e 1-27, ISSN 2472-1751 Editore: Massachusetts Institute of Technology DOI: 10.1162/netn_a_00162 Associations between moderate alcohol consumption, brain iron, and cognition in UK Biobank participants: Observational and mendelian randomization analyses Autori: Anya Topiwala; Chaoyue Wang; Klaus P. Ebmeier; Stephen Burgess; Steven Bell; Daniel F. Levey; Hang Zhou; Celeste McCracken; Adriana Roca-Fernández; Steffen E. Petersen; Betty Raman; Masud Husain; Joel Gelernter; Karla L. Miller; Stephen M. Smith; Thomas E. Nichols Pubblicato in: PLOS medicine, Numero 15491676, 2022, ISSN 1549-1676 Editore: PLOS DOI: 10.17863/cam.85375 Asymmetric thinning of the cerebral cortex across the adult lifespan is accelerated in Alzheimer’s disease Autori: James M. Roe, Didac Vidal-Piñeiro, Øystein Sørensen, Andreas M. Brandmaier, Sandra Düzel, Hector A. Gonzalez, Rogier A. Kievit, Ethan Knights, Simone Kühn, Ulman Lindenberger, Athanasia M. Mowinckel, Lars Nyberg, Denise C. Park, Sara Pudas, Melissa M. Rundle, Kristine B. Walhovd, Anders M. Fjell, René Westerhausen & The Australian Imaging Biomarkers and Lifestyle Flagship Study of Ageing Pubblicato in: Nature Communications, Numero 12, Article number: 721, 2021, ISSN 2041-1723 Editore: Nature Publishing Group DOI: 10.1038/s41467-021-21057-y È in corso la ricerca di dati su OpenAIRE... Si è verificato un errore durante la ricerca dei dati su OpenAIRE Nessun risultato disponibile
