Objectif The aim of this project is to design, synthesize and investigate the operation of synthetic molecular machines capable of performing sophisticated tasks in chemical synthesis. The molecular machines are inspired by biological systems, where substrates are shuttled between different enzymatic sites, undergoing chemical transformations at each step. Control of substrate position allows for reactions to occur in a specific sequence, with the molecular machine dictating the selectivity of each successive chemical reaction. The project both seeks to optimize the structure of the molecular machines for use as a synthetic platform and demonstrate their usefulness for synthesis and catalysis in model reactions. The successful demonstration of this concept would mark the beginning of a fundamentally new approach for the construction of molecules. Champ scientifique natural scienceschemical sciencescatalysisengineering and technologyelectrical engineering, electronic engineering, information engineeringelectronic engineeringroboticsengineering and technologyenvironmental engineeringenergy and fuelsnatural sciencesbiological sciencesbiochemistrybiomoleculesproteinsenzymes Programme(s) H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions Main Programme H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility Thème(s) MSCA-IF-2016 - Individual Fellowships Appel à propositions H2020-MSCA-IF-2016 Voir d’autres projets de cet appel Régime de financement MSCA-IF-EF-ST - Standard EF Coordinateur THE UNIVERSITY OF MANCHESTER Contribution nette de l'UE € 183 454,80 Adresse OXFORD ROAD M13 9PL Manchester Royaume-Uni Voir sur la carte Région North West (England) Greater Manchester Manchester Type d’activité Higher or Secondary Education Establishments Liens Contacter l’organisation Opens in new window Site web Opens in new window Participation aux programmes de R&I de l'UE Opens in new window Réseau de collaboration HORIZON Opens in new window Coût total € 183 454,80