Periodic Reporting for period 2 - SELFIEv2.0 (Identifying the neuronal basis of self-concept in the human medial prefrontal and medial temporal brain regions)
Okres sprawozdawczy: 2020-03-01 do 2021-02-28
The aim of this EU project funded by the Marie Skłodowska-Curie Action is to characterize the neurophysiological mechanisms of self-concept representation for the first time. We use the state-of-the-art methods of single-neuron recordings in human subjects implanted with depth electrodes for the diagnosis of epilepsy. The project is a collaboration between the Karolinska Institute in Sweden and the University of California, Los Angeles, USA.
We have collected and analyzed data from more than thirty participants and identified unique patterns of brain activity related to the encoding and retrieval of self-relevant information. These key findings have important implications for the future diagnosis and treatment of psychiatric disorders characterized by an atypical sense of self, including depression. Apart from providing novel scientific insights, the project has established new international collaborations and allowed significant transfer of knowledge.