Carbohydrate-based fine chemicals: Development of a glycosylation platform cell factory and optimization of downstream processing for the sustainable production of glycosides.

Livrables

First data management plan

Data management plan periodically updated

Third data management plan

Third data management plan periodically updated

Second data management plan

Second data management plan periodically updated

Installation of Stakeholder advisory board

"Report on output of online questionnaire of ""gender aspects in biotech jobs"""

Report on output of online questionnaire of gender aspects in biotech jobs

Publications

Second data management plan

Auteurs: Christiane Luley
Publié dans: 2019
Éditeur: European Commission

Additional file 1 of Whole cell-based catalyst for enzymatic production of the osmolyte 2-O-α-glucosylglycerol

Auteurs: Schwaiger, Katharina N.; Cserjan-Puschmann, Monika; Striedner, Gerald; Nidetzky, Bernd
Publié dans: Microbial Cell Factories, 2021, ISSN 1475-2859
Éditeur: BioMed Central Ltd.
DOI: 10.6084/m9.figshare.14385634

First data management plan

Auteurs: Christiane Luley
Publié dans: 2018
Éditeur: European Commission

Additional file 1 of Kinetic modeling of phosphorylase-catalyzed iterative β-1,4-glycosylation for degree of polymerization-controlled synthesis of soluble cello-oligosaccharides

Auteurs: Klimacek, Mario; Zhong, Chao; Nidetzky, Bernd
Publié dans: Biotechnology for Biofuels and Bioproducts, 2021
Éditeur: Springer Nature
DOI: 10.6084/m9.figshare.14767225

Installation of Stakeholder advisory board

Auteurs: Christiane Luley
Publié dans: 2018
Éditeur: European Commission

Plasmid Design for Tunable Two‐Enzyme Co‐Expression Promotes Whole‐Cell Production of Cellobiose

Auteurs: Schwaiger, Katharina N.; Voit, Alena; Dobiasová, Hana; Luley-Goedl, Christiane; Wiltschi, Birgit; Nidetzky, Bernd
Publié dans: Biotechnology Journal, 2020, ISSN 1860-7314
Éditeur: Wiley-VCH GmbH
DOI: 10.1002/biot.202000063

β-Glucan phosphorylases in carbohydrate synthesis

Auteurs: Zorica Ubiparip; Marc De Doncker; Koen Beerens; Jorick Franceus; Tom Desmet
Publié dans: Applied Microbiology and Biotechnology, Numéro 4, 2021, ISSN 0175-7598
Éditeur: Springer Verlag
DOI: 10.1007/s00253-021-11320-z

Engineering of a Thermostable Biocatalyst for the Synthesis of 2-O-Glucosylglycerol.

Auteurs: Jorick Franceus; Zorica Ubiparip; Koen Beerens; Tom Desmet
Publié dans: ChemBioChem, Numéro 2, 2021, ISSN 1439-7633
Éditeur: Wiley-VCH GmbH
DOI: 10.1002/cbic.202100192

Short-Chain Cello-oligosaccharides: Intensification and Scale-up of Their Enzymatic Production and Selective Growth Promotion among Probiotic Bacteria

Auteurs: Chao Zhong, Christina Ukowitz, Konrad J. Domig, Bernd Nidetzky
Publié dans: Journal of Agricultural and Food Chemistry, Numéro 68/32, 2020, Page(s) 8557-8567, ISSN 0021-8561
Éditeur: American Chemical Society
DOI: 10.1021/acs.jafc.0c02660

Whole cell-based catalyst for enzymatic production of the osmolyte 2- O -α-glucosylglycerol

Auteurs: Katharina N. Schwaiger; Monika Cserjan-Puschmann; Gerald Striedner; Bernd Nidetzky
Publié dans: Microbial Cell Factories, Numéro 7, 2021, ISSN 1475-2859
Éditeur: BioMed Central
DOI: 10.1186/s12934-021-01569-4

On the donor substrate dependence of group‐transfer reactions by hydrolytic enzymes: Insight from kinetic analysis of sucrose phosphorylase‐catalyzed transglycosylation

Auteurs: Mario Klimacek, Alexander Sigg, Bernd Nidetzky
Publié dans: Biotechnology and Bioengineering, Numéro 117/10, 2020, Page(s) 2933-2943, ISSN 0006-3592
Éditeur: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/bit.27471

Reducing end thiol-modified nanocellulose: Bottom-up enzymatic synthesis and use for templated assembly of silver nanoparticles into biocidal composite material

Auteurs: Chao Zhong, Krisztina Zajki-Zechmeister, Bernd Nidetzky
Publié dans: Carbohydrate Polymers, 2021, ISSN 0144-8617
Éditeur: Pergamon Press Ltd.
DOI: 10.1016/j.carbpol.2021.117772

Three-level hybrid modeling for systematic optimization of biocatalytic synthesis: α-glucosyl glycerol production by enzymatic trans-glycosylation from sucrose

Auteurs: Sigg, Alexander; Klimacek, Mario; Nidetzky, Bernd
Publié dans: Biotechnology and Bioengineering, Numéro 2, 2021, ISSN 1097-0290
Éditeur: Wiley Periodicals, LLC
DOI: 10.1002/bit.27878

Engineering cascade biocatalysis in whole cells for bottom-up synthesis of cello-oligosaccharides: flux control over three enzymatic steps enables soluble production

Auteurs: Katharina N. Schwaiger, Alena Voit, Birgit Wiltschi, Bernd Nidetzky
Publié dans: Microbial Cell Factories, 2022, ISSN 1475-2859
Éditeur: BioMed Central
DOI: 10.1186/s12934-022-01781-w

Kinetic modeling of phosphorylase-catalyzed iterative β-1,4-glycosylation for degree of polymerization-controlled synthesis of soluble cello-oligosaccharides

Auteurs: Mario Klimacek; Chao Zhong; Bernd Nidetzky
Publié dans: Biotechnology for Biofuels, Numéro 2, 2021, ISSN 2731-3654
Éditeur: BMC
DOI: 10.1186/s13068-021-01982-2

Engineering of cellobiose phosphorylase for the defined synthesis of cellotriose

Auteurs: Zorica Ubiparip, David Sáez Moreno, Koen Beerens, Tom Desmet
Publié dans: Applied Microbiology and Biotechnology, Numéro 104/19, 2020, Page(s) 8327-8337, ISSN 0175-7598
Éditeur: Springer Verlag
DOI: 10.1007/s00253-020-10820-8

Continuous process technology for glucoside production from sucrose using a whole cell-derived solid catalyst of sucrose phosphorylase.

Auteurs: Andreas Kruschitz; Linda Peinsipp; Martin Pfeiffer; Bernd Nidetzky
Publié dans: Applied Microbiology and Biotechnology, Numéro 7, 2021, ISSN 0175-7598
Éditeur: Springer Verlag
DOI: 10.1007/s00253-021-11411-x

Product solubility control in cellooligosaccharide production by coupled cellobiose and cellodextrin phosphorylase

Auteurs: Chao Zhong, Christiane Luley‐Goedl, Bernd Nidetzky
Publié dans: Biotechnology and Bioengineering, Numéro 116(9), 2019, Page(s) 2146-2155, ISSN 0006-3592
Éditeur: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/bit.27008

Sucrose Phosphorylase and Related Enzymes in Glycoside Hydrolase Family 13: Discovery, Application and Engineering

Auteurs: Jorick Franceus, Tom Desmet
Publié dans: International Journal of Molecular Sciences, Numéro 21/7, 2020, Page(s) 2526, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms21072526

Three‐Enzyme Phosphorylase Cascade Immobilized on Solid Support for Biocatalytic Synthesis of Cello−oligosaccharides

Auteurs: Chao Zhong, Božidar Duić, Juan M. Bolivar, Bernd Nidetzky
Publié dans: ChemCatChem, Numéro 12/5, 2020, Page(s) 1350-1358, ISSN 1867-3880
Éditeur: Wiley - VCH Verlag GmbH & CO. KGaA
DOI: 10.1002/cctc.201901964

Downstream processing technologies in the biocatalytic production of oligosaccharides

Auteurs: Andreas Kruschitz, Bernd Nidetzky
Publié dans: Biotechnology Advances, Numéro 43, 2020, Page(s) 107568, ISSN 0734-9750
Éditeur: Elsevier BV
DOI: 10.1016/j.biotechadv.2020.107568

Removal of glycerol from enzymatically produced 2-α-d-glucosyl-glycerol by discontinuous diafiltration

Auteurs: Andreas Kruschitz, Bernd Nidetzky
Publié dans: Separation and Purification Technology, Numéro 241, 2020, Page(s) 116749, ISSN 1383-5866
Éditeur: Pergamon Press Ltd.
DOI: 10.1016/j.seppur.2020.116749

Three‐Enzyme Phosphorylase Cascade for Integrated Production of Short‐Chain Cellodextrins

Auteurs: Chao Zhong, Bernd Nidetzky
Publié dans: Biotechnology Journal, Numéro 15/3, 2020, Page(s) 1900349, ISSN 1860-6768
Éditeur: Wiley - VCH Verlag GmbH & CO. KGaA
DOI: 10.1002/biot.201900349

Reactive extraction of fructose for efficient separation of sucrose-derived glucosides produced by enzymatic glycosylation

Auteurs: Kruschitz, Andreas; Nidetzky, Bernd
Publié dans: Green Chemistry, Numéro 22(15), 2020, ISSN 1463-9270
Éditeur: Royal Society of Chemistry

Internal reporting on process optimization measures: combination of economic and environmental aspects

Auteurs: Rudolf Grünbichler, Barbara Petschacher, René Kollmann, Alexander Passer, Stefan Grbenic
Publié dans: FACTA UNIVERSITATIS, Series: Economics and Organization, 2021, ISSN 2406-050X
Éditeur: University of Nis
DOI: 10.22190/fueo210622030g

Precision synthesis of reducing-end thiol-modified cellulose enabled by enzyme selection

Auteurs: Chao Zhong; Bernd Nidetzky
Publié dans: Polymer Journal, Numéro 7, 2021, ISSN 0032-3896
Éditeur: Nature Publishing Group
DOI: 10.1038/s41428-021-00599-4

Phosphorylase-catalyzed bottom-up synthesis of short-chain soluble cello-oligosaccharides and property-tunable cellulosic materials

Auteurs: Bernd Nidetzky, Chao Zhong
Publié dans: Biotechnology Advances, 2020, Page(s) 107633, ISSN 0734-9750
Éditeur: Elsevier BV
DOI: 10.1016/j.biotechadv.2020.107633

Biocatalytic Production of 2-α-d-Glucosyl-glycerol for Functional Ingredient Use: Integrated Process Design and Techno-Economic Assessment

Auteurs: Andreas Kruschitz; Bernd Nidetzky
Publié dans: ACS Sustainable Chemistry & Engineering, 2022, ISSN 2168-0485
Éditeur: American Chemical Society
DOI: 10.1021/acssuschemeng.1c07210

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