Objectif Bovine spongiform encephalopathy (BASE), is causing concern for both animal and human health. It was first identified in the United Kingdom in 1986. Sporadic cases have been recognized in, France, Ireland, Switzerland and Oman. The study is to confirm or exclude the suspicion that BSE occurs in other European Community (EC).A diagnostic network for the surveillance of BSE has been set up in the 5 EC States using standard histopathological techniques. In total, 1104 brains from ruminants with neurological disorders have been examined. The distribution of these was 145 in Germany, 245 in Belgium, 398 in Italy, 49 in Luxembourg and 267 in France. So far, the investigation has resulted in the confirmation of the absence of BSE cases in Germany, Belgium, Italy and Luxembourg and the confirmation of five cases of BSE in France. Lesions corresponding to various bovine diseases were seen in the BSE negative cow brains. These diseases included malignant catarrhal fever, listeriosis, bovine vesicular disease, Aujeszky's disease and others.BSE is causing great concern for both animal and human health : in the UK from November 1985 up till 6 December 1991, 42 337 cases were diagnosed in 14 969 farms. The possibility that BSE occurs in other countries has meanwhile been confirmed by 9 cases in Switzerland, 4 cases in France and 2 cases in Oman. Therefore, during two CEC organised training courses at the Central Veterinary Laboratory in Weybridge, one or more researchers per Member State have been trained to use standard histopathological procedures. In five Member States (B, F, D, I and L) where rabies is endemic, brains from cattle with neurological disorders are routinely examined on rabies. The rabies-negative brains are the target samples by excellence to test for BSE. The project will allow to establish a surveillance network for the control of BSE in the five rabies infected Member States. The aim of the project is to confirm or to exclude the suspicion that BSE occurs in these Member States and to have well experienced workers and an elaborated diagnosis infrastructure ready in case of BSE outbreaks in one or more countries. Champ scientifique agricultural sciencesanimal and dairy sciencedomestic animalsanimal husbandrymedical and health sciencesbasic medicineneurology Programme(s) FP2-CAMAR - Research and technological development programme (EEC) in the field of competitiveness of agriculture and management of agricultural resources, 1989-1993 Thème(s) Data not available Appel à propositions Data not available Régime de financement Data not available Coordinateur National Instituut voor Diergeneeskundig Onderzoek Contribution de l’UE Aucune donnée Adresse Groeselenberg 99 1180 BRUSSELS Belgique Voir sur la carte Coût total Aucune donnée Participants (6) Trier par ordre alphabétique Trier par contribution de l’UE Tout développer Tout réduire Bundesministerium für Ernährung, Landwirtschaft und Forsten Allemagne Contribution de l’UE Aucune donnée Adresse 5300 Bonn Voir sur la carte Coût total Aucune donnée Centre National d'Études Vétérinaires et Alimentaires (CNEVA) France Contribution de l’UE Aucune donnée Adresse 22 rue Pierre Curie 94703 Maisons Alfort Voir sur la carte Coût total Aucune donnée Dr J. Van Bekkum Pays-Bas Contribution de l’UE Aucune donnée Adresse Wildban 8 8222AG LELYSTAD Voir sur la carte Coût total Aucune donnée Laboratoire de Medecine Veterinaire de l'Etat Luxembourg Contribution de l’UE Aucune donnée Adresse Av. Gaston Diderich 54 1420 LUXEMBOURG Voir sur la carte Coût total Aucune donnée Università degli Studi di Torino Italie Contribution de l’UE Aucune donnée Adresse Via Nizza 52 10126 Torino Voir sur la carte Coût total Aucune donnée École Nationale Vétérinaire de Maisons Alfort France Contribution de l’UE Aucune donnée Adresse 7 avenue du Général de Gaulle 94704 Maisons Alfort Voir sur la carte Coût total Aucune donnée