Description du projet
Donner les moyens nécessaires à la prochaine génération de neurobiologistes
Le cerveau est l’organe le plus complexe du corps humain: il reçoit des informations provenant de notre environnement et les intègre dans la planification et l’exécution des actions appropriées. Les principes des communications entre les différentes zones du cerveau, servant à combiner les informations sensorielles avec le contrôle moteur et les fonctions exécutives, restent en grande partie méconnus. Le projet In2PrimateBrains, financé par l’UE, entend combler ce manque de connaissances en formant la prochaine génération de chercheurs avec des méthodes de pointe dans les secteurs industriel, clinique et universitaire afin de soutenir les recherches futures dans ce domaine. Les chercheurs en formation étudieront le cerveau de primates non humains, le modèle le plus proche du cerveau humain, apportant ainsi des informations importantes sur les dynamiques locales et à longue portée intervenant dans les communications jusqu’au niveau des neurones individuels.
Objectif
In2PrimateBrains proposes a highly competitive training-through-research program dedicated to the study of neuronal intra- and
inter-areal communication in non-human primate (NHP) brains. This program will empower the next generation of
researchers with best practices and cutting edge methodologies for studying complex neuronal activity from multiple brain
areas and across cortical layers. Our core scientific goals are to identify common and specific bottom-up and top-down
communication principles across NHP brain networks for vision, motor control and executive functions. These functions are
especially well developed in primates, and we propose to study them in a brain model as close as possible to the human
brain: the NHP brain. Critically, detailed insights into the local- and long-range dynamics of communication, down to the
single-neuron level and at millisecond precision, necessitate invasive recording, stimulation and inactivation techniques
precluding human investigations. The project entails 9 work packages with well-defined tasks to ensure success in our
research and training objectives. We propose tailored research training by world-leading European researchers from the
academic, clinical and industrial sectors. This will be accompanied by a comprehensive program of network-wide training
events including thematic workshops in essential research-related skills and soft-skill training sessions to ensure successful
careers in public or private sectors. The direct experience and acquired expertise in state-of-the-art NHP research and
technology development in different environments will drive our ESRs to pursue international, interdisciplinary and
intersectoral careers. In a highly competitive international environment, In2PrimateBrains will ensure that Europe remains at the
forefront of primate brain research in health and disease with scientists trained by the highest scientific, methodological and
ethical standards.
Champ scientifique
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Régime de financement
MSCA-ITN - Marie Skłodowska-Curie Innovative Training Networks (ITN)Coordinateur
13284 Marseille
France