Projektbeschreibung
Stärkung der Mikrobiomforschung zur Verbesserung von menschlicher Gesundheit und Wohlbefinden
Obwohl Europa in der Mikrobiomforschung bereits führend ist, muss es in wesentlichen Punkten noch international konsensfähig werden, um der gesellschaftlichen Erwartung gerecht zu werden. Das EU-finanzierte Projekt IHMCSA untersucht, über welche Interventionen die Nährstoffversorgung und Gesundheit des menschlichen Mikrobioms verbessert werden kann. Unter Einbeziehung wichtiger Interessengruppen und Vertreter aller Akteure, u. a. der Bevölkerung, wird das Projekt vorhandenes Material sichten und erforderliche Maßnahmen für Innovationen ermitteln. Zudem soll ein Konsens zu Prioritäten und Mitteln in der künftigen Mikrobiomforschung sowie der Umsetzung von Forschungsergebnissen erarbeitet werden.
Ziel
Humans are microbial, living in close functional interaction with their skin and mucosal microbiomes. Human-microbes interplay has proven essential for the maintenance of health and well-being and profiling of microbiomes will become an essential feature of the personalized preventive nutrition and medicine of tomorrow. Europe has gained a leading position in microbiome science and yet to fulfill societal expectations, an international consensus will be essential on key aspects. These include i) clinical trial design as well as analytical standards, ii) definitions of healthy microbiomes as a function of numerous factors, accounting for confounders, iii) means of demonstrating causality of altered host-microbes interactions in diseases and iv) processes for the development of clinically relevant, validated biomarkers. The International Human Microbiome Concertation and Support Action (IHMCSA) will tackle all necessary steps to open the perspective of managing nutrition and health of the microbial human. Involving key stakeholders representing the multiplicity of actors concerned, including citizens, IHMCSA will map existing material, delineate necessary steps and pathways for innovation and build consensus on priorities and means for the future of microbiome science and its translation. This will lead to recommendations, validated by an international Strategic Steering Committee as well as academies of medicine of the world, directed to the European Commission, international research programmes, funding and regulatory agencies and decision makers of health systems. To ensure sustainability of the proposed measures, IHMCSA will promote unified repositories for sharing standards, SOPs and data, and contribute to the structuration of the European Microbiome Centers Consortium with a role in gathering world microbiome networks of excellence. With IHMCSA, human-associated microbiomes will be recognized for their true value in contributing to secure the future of mankind.
Wissenschaftliches Gebiet
Schlüsselbegriffe
Programm/Programme
Thema/Themen
Aufforderung zur Vorschlagseinreichung
Andere Projekte für diesen Aufruf anzeigenUnterauftrag
H2020-SC1-2020-Single-Stage-RTD
Finanzierungsplan
CSA - Coordination and support actionKoordinator
75007 Paris
Frankreich