Cel Development of a series of ecologically relevant toxicity tests to assess under realistic exposure scenarios the full breadth of responses of aquatic organisms to chemical contaminants.METIER will build upon the results obtained within a preceding project in the STEP Programme (Contract EV5V-CT91-0009) which involved the development of a standard flow-through exposure system and a series of toxicity tests linked to a mechanistic physiological model of contaminant effects in the aquatic environment, to support the development of regulatory guidelines for poorly water-soluble compounds (pre-normative research) in relation to EC Directives 76/548/EEC and 88/379/EEC.Specifically METIER will- further develop the Daphnia magna model, including transfer options to other species (e.g. Carassius auratus, Chironomus riparius);- investigate an artificial sediment matrix to allow manipulations of the bioavailability of poorly water-soluble compounds, and the development of a standardised sediment toxicity test using Chironomus riparius;- examine the role of the binding of contaminants in the water column on particulate matter for the effective exposure estimates;- continue developing the flow-through system for the testing of "difficult" substances;- validate the test system using two EC Priority List I chemicals (3,4-dichloroaniline and parathion);- develop rapid-test endpoints (e.g. feeding inhibition) which can be mechanistically linked to long-term life-cycle endpoints (e.g. inhibition of reproduction) using model simulations, with potential application in effluent "end-of-pipe" testing. Dziedzina nauki natural sciencesbiological sciencesecologyecosystemsnatural sciencesearth and related environmental scienceshydrologylimnology Program(-y) FP3-ENV 1C - Specific research and technological development programme (EEC) in the field of the environment, 1990-1994 Temat(-y) 040204 - Risks to health and the environment from chemical substances Zaproszenie do składania wniosków Data not available System finansowania CSC - Cost-sharing contracts Koordynator Universidade de Coimbra Wkład UE Brak danych Adres Largo Marquês de Pombal 3049 Coimbra Portugalia Zobacz na mapie Koszt całkowity Brak danych Uczestnicy (3) Sortuj alfabetycznie Sortuj według wkładu UE Rozwiń wszystko Zwiń wszystko Technische Universität Berlin Niemcy Wkład UE Brak danych Adres Goerzallee 253 14167 Berlin Zobacz na mapie Koszt całkowity Brak danych UNIVERSITY OF SHEFFIELD Zjednoczone Królestwo Wkład UE Brak danych Adres Western Bank S10 2TN SHEFFIELD Zobacz na mapie Koszt całkowity Brak danych University of Stirling Zjednoczone Królestwo Wkład UE Brak danych Adres University of Stirling FK9 4LA Stirling Zobacz na mapie Koszt całkowity Brak danych