Obiettivo
Due to the systematic sequencing projects, the gap between the number of available protein sequences and structures increases, and the need for developing global proteomic programs becomes crucial. In this context, the prediction of new folds from scratch and the identification of characteristic folding fragments are necessary steps towards rational protein engineering and the elucidation of diseases related to misfolded structures. All the groups involved develop in silicon methods for determining protein structural subunits likely to correspond to key elements in the folding process. Our objective is to combine the expertise of the different groups and to transfer ideas and results in view of improving the efficiency of the individual approaches and establishing a synergetic prediction scheme of protein structure from sequence and conversely.
Campo scientifico
Invito a presentare proposte
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CON - Coordination of research actionsCoordinatore
75252 PARIS
Francia