The impact of developmental exposure to weak (environmental) estrogens on the incidence of diseases in target organs later in life

Informations projet

ESTROGENS AND DISEAS

N° de convention de subvention: QLK4-CT-2000-00305

Projet clôturé

Date de début 1 Janvier 2001

Date de fin 31 Decembre 2004

Financé au titre de

• Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002

Coût total € 1 550 000,00

Contribution de l’UE € 1 550 000,00

Coordonné par

NETHERLANDS INSTITUTE FOR DEVELOPMENTAL BIOLOGY
Netherlands

Objectif

The incidence of cancer is increasing steadily in tissues that are regulated by estrogens. It has been proposed that the increased cancer incidence but also fertility problems in wildlife and humans is caused by an increased exposure to environmental compounds that mimic endogenous estrogens. In the current project we will perform model studies to determine the potential impact of developmental exposure to weak estrogens on the incidence of diseases in the mammary gland, testis, prostate, ovary and brain. The project aims to improve current testing strategies, and provide molecular markers that can be used in clinical research to quantify the involvement of dietary and environmental estrogens in the ethnology of major human diseases.

Champ scientifique

• social sciences › sociology › anthropology › ethnology
• social sciences › sociology › demography › fertility
• medical and health sciences › clinical medicine › oncology

Programme(s)

• FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002

Thème(s)

• 1.1.1.-4. - Key action Environment and Health

Appel à propositions

Data not available

Régime de financement

CSC - Cost-sharing contracts

Coordinateur

NETHERLANDS INSTITUTE FOR DEVELOPMENTAL BIOLOGY

• Contribution de l’UE: Aucune donnée
• Adresse: Uppsalalaan 8 ; 3584 CT UTRECHT ; Pays-Bas
• Coût total: Aucune donnée

Participants (4)

COPENHAGEN UNIVERSITY HOSPITAL

Danemark

• Contribution de l’UE: Aucune donnée
• Adresse: Blegdamsvej 9 ; 2100 KOEPENHAGEN
• Coût total: Aucune donnée

JOHANNES GUTENBERG UNIVERSITAET MAINZ

Allemagne

• Contribution de l’UE: Aucune donnée
• Adresse: Staudinger Weg 7 ; 55099 MAINZ
• Coût total: Aucune donnée

KAROLINSKA INSTITUTE

Suède

• Contribution de l’UE: Aucune donnée
• Adresse: Novum Huddinge Sjukhus ; 141 86 Huddinge
• Coût total: Aucune donnée

UTRECHT UNIVERSITY

Pays-Bas

• Contribution de l’UE: Aucune donnée
• Adresse: Sorbonnelaan 16 ; 3584 CA UTRECHT
• Coût total: Aucune donnée