Objective ASYRING will improve information regarding the environmental levels of pollutants, their biological effects as measured with innovative tools to aquatic species and for mammalian risk assessment. It aims to develop and validate novel non-invasive methods for the detection of known and new biomarkers of endocrine disrupters. (Ends) directly in the mucus of aquatic species. Short/long term and low dose exposures to endocrine disrupting chemicals will be investigated both in aquatic species and mammals. In parallel, integrated testing in vitro protocols will permit a wider understanding and evaluation of effects and new instrumental analytical techniques will be developed and validated for easier and more complete detection of chemicals in water and biota. Quantitative structure-activity relationships (Tsars) for the prediction of chemicals able to elicit endocrine disruption and quantitative activity-activity relationships (Quarts) to extrapolate the response of different experimental models will be compared with test data developed in this project. The final aim will be to extend mathematical models to human toxicity. Fields of science natural sciencesbiological scienceszoologymammalogynatural sciencesmathematicsapplied mathematicsmathematical model Programme(s) FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002 Topic(s) 1.1.1.-4. - Key action Environment and Health Call for proposal Data not available Funding Scheme CSC - Cost-sharing contracts Coordinator N/A EU contribution No data Address See on map Total cost No data Participants (7) Sort alphabetically Sort by EU Contribution Expand all Collapse all BIOSENSE LABORATORIES A/S Norway EU contribution No data Address Thromohlensgt. 55 5008 BERGEN See on map Total cost No data FORSCHUNGSVERBUND BERLIN E.V. Germany EU contribution No data Address Mueggelseedamm 310 12587 BERLIN See on map Total cost No data LIVERPOOL JOHN MOORES UNIVERSITY United Kingdom EU contribution No data Address BYROM STREET L3 3AF LIVERPOOL See on map Total cost No data MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH Italy EU contribution No data Address 62,Via Eritrea 62 20157 MILANO See on map Total cost No data NATIONAL RESEARCH COUNCIL OF ITALY Italy EU contribution No data Address via della Mornera 25 20147 MILANO See on map Total cost No data UNIVERSITE DE MONS-HAINAUT. Belgium EU contribution No data Address Place du Parc 20 MONS-BERGEN See on map Links Website Opens in new window Total cost No data UNIVERSITY OF BERGEN Norway EU contribution No data Address Thormohlensgt. 55 5008 BERGEN See on map Total cost No data