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Development of environmental modules for evaluation of toxicity of pesticide residues in agriculture

Objective

DEMETRA' s objective is to produce software for toxicity prediction of pesticides and related compounds, for evaluation within the Dossier for pesticide registration. We will involve end-users from government and industry and ecotoxicologists to get a sound basis. Suitable data sets will be defined, with pesticides and their toxicity values in 5 organisms. We will calculate chemical descriptors of pesticides. We will develop many models using advanced computational tools, like multivariate analysis, neural networks, fuzzy logic, machine learning, genetic algorithms, etc. We will combine the most successful models within a hybrid system. This process will be done in parallel for the 5 endpoints. The so obtained 5 hybrid systems will be put on the web for free access. Further dissemination will be obtained within a workshop.

Call for proposal

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Coordinator

MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH
EU contribution
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Address
62,Via Eritrea 62
20157 MILANO
Italy

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Total cost
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Participants (5)