Objective
"The aim of this ITN is to promote research and training in the field of epigenetics associated with human disease. Expression of imprinted genes is mono-allelic and gamete of origin-dependent. This is due to different epigenetic modifications present on the maternal and paternal chromosomes. Failure in normal establishment, maintenance or erasure of these marks results in gene dosage dysregulation and Imprinting Disorders (IDs). This ITN brings together different expertise from both public and private sectors with the aim of investigating the physiology and pathology of Genomic Imprinting. We propose to define mechanisms, molecular factors and pathways regulating DNA-methylation and chromatin dynamics involved in gene expression control in human health and disease. This concerted approach has the potential to identify new and more effective diagnostic, preventive and therapeutic strategies for IDs, and more generally to elucidate roles and origin of epigenetic mutations in human pathologies, including common diseases.
Early stage (ESRs) and experienced researchers (ERs) will have access to a range of cutting-edge methodologies to enable the application of integrated multidisciplinary strategies to analyse epigenetic phenomena. The excellent scientific and educational environment and the intense public-private sector collaboration will promote high-level training of the young researchers. The ESRs and ERs will acquire experience and expertise in a variety of disciplines, including molecular, cellular and developmental biology, genomics, bioinformatics, chromatin dynamics and epigenetics and phenotypic analysis, and state-of-the-art methodologies such as gene targeting, stem cell culture, epigenetic and chromatin technologies, and massively parallel sequencing. Hence, this ITN will generate a new cohort of scientists trained in contemporary post-genomic biology and able to apply advanced technological tools to investigate human disease in both academia and industry."
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences developmental biology
- medical and health sciences medical biotechnology cells technologies stem cells
- medical and health sciences basic medicine pathology
- medical and health sciences basic medicine physiology
- natural sciences biological sciences genetics epigenetics
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-2011-ITN
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
00185 Roma
Italy
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.