Objective "The aim of this ITN is to promote research and training in the field of epigenetics associated with human disease. Expression of imprinted genes is mono-allelic and gamete of origin-dependent. This is due to different epigenetic modifications present on the maternal and paternal chromosomes. Failure in normal establishment, maintenance or erasure of these marks results in gene dosage dysregulation and Imprinting Disorders (IDs). This ITN brings together different expertise from both public and private sectors with the aim of investigating the physiology and pathology of Genomic Imprinting. We propose to define mechanisms, molecular factors and pathways regulating DNA-methylation and chromatin dynamics involved in gene expression control in human health and disease. This concerted approach has the potential to identify new and more effective diagnostic, preventive and therapeutic strategies for IDs, and more generally to elucidate roles and origin of epigenetic mutations in human pathologies, including common diseases.Early stage (ESRs) and experienced researchers (ERs) will have access to a range of cutting-edge methodologies to enable the application of integrated multidisciplinary strategies to analyse epigenetic phenomena. The excellent scientific and educational environment and the intense public-private sector collaboration will promote high-level training of the young researchers. The ESRs and ERs will acquire experience and expertise in a variety of disciplines, including molecular, cellular and developmental biology, genomics, bioinformatics, chromatin dynamics and epigenetics and phenotypic analysis, and state-of-the-art methodologies such as gene targeting, stem cell culture, epigenetic and chromatin technologies, and massively parallel sequencing. Hence, this ITN will generate a new cohort of scientists trained in contemporary post-genomic biology and able to apply advanced technological tools to investigate human disease in both academia and industry." Fields of science medical and health sciencesmedical biotechnologycells technologiesstem cellsnatural sciencesbiological sciencesgeneticsmutationmedical and health sciencesbasic medicinepathologymedical and health sciencesbasic medicinephysiologynatural sciencesbiological sciencesgeneticsepigenetics Programme(s) FP7-PEOPLE - Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) Topic(s) FP7-PEOPLE-2011-ITN - Marie-Curie Action: "Initial Training Networks" Call for proposal FP7-PEOPLE-2011-ITN See other projects for this call Funding Scheme MC-ITN - Networks for Initial Training (ITN) Coordinator CONSIGLIO NAZIONALE DELLE RICERCHE EU contribution € 696 689,98 Address PIAZZALE ALDO MORO 7 00185 Roma Italy See on map Region Centro (IT) Lazio Roma Activity type Research Organisations Administrative Contact Alfredo Di Giacomo (Mr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data Participants (9) Sort alphabetically Sort by EU Contribution Expand all Collapse all THE BABRAHAM INSTITUTE United Kingdom EU contribution € 553 201,99 Address Babraham Hall CB22 3AT Cambridge See on map Region East of England East Anglia Cambridgeshire CC Activity type Research Organisations Administrative Contact Caroline Edmonds (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data THE UNIVERSITY OF BIRMINGHAM United Kingdom EU contribution € 271 100,01 Address Edgbaston B15 2TT Birmingham See on map Region West Midlands (England) West Midlands Birmingham Activity type Higher or Secondary Education Establishments Administrative Contact May Chung (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE United Kingdom EU contribution € 271 100,01 Address TRINITY LANE THE OLD SCHOOLS CB2 1TN Cambridge See on map Region East of England East Anglia Cambridgeshire CC Activity type Higher or Secondary Education Establishments Administrative Contact Renata Schaeffer (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS France EU contribution € 277 195,01 Address RUE MICHEL ANGE 3 75794 Paris See on map Region Ile-de-France Ile-de-France Paris Activity type Research Organisations Administrative Contact Jocelyn Mere (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE France EU contribution € 538 992,00 Address RUE DE TOLBIAC 101 75654 Paris See on map Region Ile-de-France Ile-de-France Paris Activity type Research Organisations Administrative Contact Isabelle Verdier (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE Switzerland EU contribution € 254 681,00 Address BATIMENT CE 3316 STATION 1 1015 Lausanne See on map Region Schweiz/Suisse/Svizzera Région lémanique Vaud Activity type Higher or Secondary Education Establishments Administrative Contact Didier Trono (Prof.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data KOBENHAVNS UNIVERSITET Denmark EU contribution € 306 748,00 Address NORREGADE 10 1165 Kobenhavn See on map Region Danmark Hovedstaden Byen København Activity type Higher or Secondary Education Establishments Administrative Contact Ivan Kristoffersen (Mr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data FUNDACIO CENTRE DE REGULACIO GENOMICA Spain EU contribution € 238 104,00 Address CARRER DOCTOR AIGUADER 88 08003 Barcelona See on map Region Este Cataluña Barcelona Activity type Research Organisations Administrative Contact Mariana Morlans (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data DIAGENODE Belgium EU contribution € 255 068,00 Address RUE DU BOIS SAINT JEAN 3 LIEGE PARK SCIENCE 4102 Seraing See on map Region Région wallonne Prov. Liège Arr. Liège Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Leon Etienne (Mr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data