Objective With a share of 38%, orthopaedic and traumatology (O&T) are the worldwide leading markets of implanted biomaterials, involving millions of new patients each year at an increasing trend. Infection related to implanted medical devices is directly related to bacterial capability to establish multilayered, highly structured biofilms on artificial surfaces. Bacterial infections due to implanted biomaterials represent the most devastating complication in O&T, involving millions of European citizens. Aim of the present research is to develop, validate and bring to the market a disposable coating of implanted biomaterial (Implant Disposable Antibacterial Coating, I.D.A.C.). The device, based on a novel, proprietary, resorbable hydrogel, would act as a fast resorbable local delivery carrier of antibiofilm and antibacterial compounds. The active drug (antibiofilm and antibiotic agents) will be mixed at the time of the hydrogel application, allowing the correct choice for any given patient, reducing regulatory requirements, improving storage life and versatility. In particular, I.D.A.C. will be tested as a resorbable carrier of drugs (e.g.: N-acetylcisteine and its derivatives, serratia peptidase and other peptides, etc.) already known from our studies for having excellent antibiofilm properties, while others are able to by-pass the intact biofilm barrier and kill the underlying bacteria, when locally administered. The final purpose of the present research is to set a novel approach to early control of biofilm formation,to prevent bacterial colonization of implanted material and to treat established implant-related infections and chronic wounds, without any risk of inducing new drug resistance and alter the environment. The research will be conducted under the aegis of the European Bone and Joint Infection Society and the European Hip Society, through a network of upper standard European research and clinical centers and experienced SMEs from eight Countries around Europe. Fields of science natural sciencesbiological sciencesmicrobiologybacteriologymedical and health sciencesbasic medicinepharmacology and pharmacydrug resistanceengineering and technologymaterials engineeringcoating and filmsmedical and health sciencesclinical medicineorthopaedicsengineering and technologyindustrial biotechnologybiomaterials Programme(s) FP7-HEALTH - Specific Programme "Cooperation": Health Topic(s) HEALTH.2011.2.3.1-5 - Development of tools to control microbial biofilms with relevance to clinical drug resistance Call for proposal FP7-HEALTH-2011-two-stage See other projects for this call Funding Scheme CP-FP - Small or medium-scale focused research project Coordinator NOVAGENIT SRL EU contribution € 658 138,00 Address VIALE TRENTO 115/117 38017 MEZZOLOMBARDO Italy See on map Region Nord-Est Provincia Autonoma di Trento Trento Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Total cost No data Participants (11) Sort alphabetically Sort by EU Contribution Expand all Collapse all KENTRO EREVNAS TECHNOLOGIAS KAI ANAPTYXIS THESSALIAS Participation ended Greece EU contribution No data Address TECHNOLOGIKO PARKO A VIPE 38500 VOLOS See on map Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Total cost No data ADLER ORTHO FRANCE France EU contribution € 204 174,00 Address ROUTE DE LA COTE D AZUR RUE DE LA BELLE DU CANET ARTEPARC BAT F LE CANET 13590 MEYREUIL See on map Region Provence-Alpes-Côte d’Azur Provence-Alpes-Côte d’Azur Bouches-du-Rhône Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Total cost No data ADLER ORTHO S.P.A. Italy EU contribution € 245 675,00 Address VIA DELL INNOVAZIONE 9 20032 CORMANO MI See on map Region Nord-Ovest Lombardia Milano Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Total cost No data BELGAFIX Belgium EU contribution € 194 874,00 Address RUE LONGUE 286 1620 DROGENBOS See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Total cost No data CF CONSULTING FINANZIAMENTI UNIONE EUROPEA SRL Italy EU contribution € 123 061,00 Address Via Giuseppe Mussi 1 20154 Milano See on map Region Nord-Ovest Lombardia Milano Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data BONALIVE BIOMATERIALS OY Finland EU contribution € 148 000,00 Address BIOLINJA 12 20750 TURKU See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data ETHNIKO KENTRO EREVNAS KAI TECHNOLOGIKIS ANAPTYXIS Greece EU contribution € 288 990,00 Address CHARILAOU THERMI ROAD 6 KM 57001 Thermi Thessaloniki See on map Region Βόρεια Ελλάδα Κεντρική Μακεδονία Θεσσαλονίκη Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Total cost No data OSPEDALE GALEAZZI SPA Italy EU contribution € 478 126,00 Address VIA CRISTINA BELGIOIOSO 173 20152 Milano See on map Region Nord-Ovest Lombardia Milano Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Total cost No data UNIVERSITAIR MEDISCH CENTRUM UTRECHT Netherlands EU contribution € 263 580,00 Address HEIDELBERGLAAN 100 3584 CX Utrecht See on map Region West-Nederland Utrecht Utrecht Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Total cost No data UNIVERSITATSKLINIKUM HEIDELBERG Germany EU contribution € 223 647,00 Address IM NEUENHEIMER FELD 672 69120 Heidelberg See on map Region Baden-Württemberg Karlsruhe Heidelberg, Stadtkreis Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Total cost No data KATHOLIEKE UNIVERSITEIT LEUVEN Belgium EU contribution € 171 735,00 Address OUDE MARKT 13 3000 Leuven See on map Region Vlaams Gewest Prov. Vlaams-Brabant Arr. Leuven Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Total cost No data