Obiettivo BRASINOEU aims to study the translocation and nanosafety issues of engineered metal oxide nanoparticles (NPs).The new scientific and technology developments of nanotechnology require a deeper knowledge of the effects of nanotechnology based products on human health. This knowledge is fundamental for the development of nanotechnology and to achieve its full acceptance. The concept of “safe by design” is based on the application of nanosafety to design the nanomaterials in order to prevent or reduce their possible harm to humans and the environment. The project encompass the synthesis of metal oxide NPs, with a focus on magnetic oxides, their surface modification and post modification in biological fluids; immunological and genotoxicity studies, and translocation studies both “in vitro” and “in vivo”. The project will seek to establish relationships between designed NP properties and their translocation at cellular and body level as well as their immune- and genotoxic response. This is a fundamental issue for the safe design of NPs. Also, the toxicological response will be studied as a function of the uptake dose of NPs. At cellular level a battery of techniques will be applied for localization and quantification of NPs: Transmission Electron Microscopy, Raman, Confocal Microscopy, Ion Beam Microscopy, etc. Positron Emission Tomography and Magnetic Resonance Imaging will be employed for biodistribution and quantification studies in animal models. BRASINOU is formed by an international team with the required and complementary expertise to address the proposed work from an international and multidisciplinary perspective. The project gathers internationally recognized groups in immunology, genotoxicity, nanoparticle synthesis, surface chemistry, biophysics, imaging and materials science. The complementary of the groups involved in the project will help to develop new highly skilled professional and scientific horizontal connections. Campo scientifico natural scienceschemical sciencesinorganic chemistryinorganic compoundsnatural sciencesphysical sciencesopticsmicroscopyelectron microscopynatural sciencesbiological sciencesbiophysicsnatural sciencesphysical sciencesopticsmicroscopyconfocal microscopyengineering and technologynanotechnologynano-materials Programma(i) FP7-PEOPLE - Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) Argomento(i) FP7-PEOPLE-2012-IRSES - Marie Curie Action "International Research Staff Exchange Scheme" Invito a presentare proposte FP7-PEOPLE-2012-IRSES Vedi altri progetti per questo bando Meccanismo di finanziamento MC-IRSES - International research staff exchange scheme (IRSES) Coordinatore UNIVERSITAET LEIPZIG Contributo UE € 98 700,00 Indirizzo RITTERSTRASSE 26 04109 Leipzig Germania Mostra sulla mappa Regione Sachsen Leipzig Leipzig Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Irina Estrela-Lopis (Dr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato Partecipanti (4) Classifica in ordine alfabetico Classifica per Contributo UE Espandi tutto Riduci tutto ASOCIACION CENTRO DE INVESTIGACION COOPERATIVA EN BIOMATERIALES- CIC biomaGUNE Spagna Contributo UE € 199 500,00 Indirizzo PASEO MIRAMON 182, PARQUE TECNOLOGICO DE SAN SEBASTIAN EDIFICIO EMPRESARIAL C 20009 San Sebastian Mostra sulla mappa Regione Noreste País Vasco Gipuzkoa Tipo di attività Research Organisations Contatto amministrativo Alfonso Egaña (Mr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato INSTYTUT FIZYKI POLSKIEJ AKADEMII NAUK Polonia Contributo UE € 33 600,00 Indirizzo AL LOTNIKOW 32/46 02 668 Warszawa Mostra sulla mappa Regione Makroregion województwo mazowieckie Warszawski stołeczny Miasto Warszawa Tipo di attività Research Organisations Contatto amministrativo Ewa Mosiniewicz-Szablewska (Dr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato TYOTERVEYSLAITOS Finlandia Contributo UE € 65 100,00 Indirizzo TOPELIUKSENKATU 41 B 00250 Helsinki Mostra sulla mappa Regione Manner-Suomi Helsinki-Uusimaa Helsinki-Uusimaa Tipo di attività Research Organisations Contatto amministrativo Julia Catalán (Dr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato WARSZAWSKI UNIWERSYTET MEDYCZNY Polonia Contributo UE € 31 500,00 Indirizzo UL. ZWIRKI I WIGURY 61 02 091 Warszawa Mostra sulla mappa Regione Makroregion województwo mazowieckie Warszawski stołeczny Miasto Warszawa Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Joanna Sobczak (Mrs.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato
