Objetivo CLINICAL NEEDEvery year in the EU ~45,300 and 330,000 women are diagnosed with ovarian and breast cancer respectively & 28,800 and 90,000 of these two groups of women will die as a consequence of these diseases. Currently there are no tools available that allow for:a) Effective screening of ovarian and/or breast cancer of sufficient sensitivity and specificity to avoid potential over-diagnosis, or;b) Stratification of patients into optimal personalised therapy regimes in ovarian/breast cancer.EpiFemCare ADVANCESProgress in personalised cancer medicine will only be possible with the development of bioassays involving the analysis of easy accessible biomaterials that contain stable target molecules reflective of disease. We will establish and clinically validate a series of blood tests based upon DNA methylation technology that will facilitate both early detection and prediction of therapeutic outcome in breast and ovarian cancer.CONSORTIUMOur pan-European academic-industrial consortium demonstrates diverse clinical, scientific & industrial expertise. We have access to the latest state of the art technologies and, integrally, the best available cohort and clinical trial sample sets required to ensure the success of the EpiFemCare program. GATC-Biotech and Genedata are Europe’s leading providers of DNA sequencing and bioinformatics for biomarker development and have developed serum DNA based prenatal tests. The clinical partners have access to unique cohort and clinical samples collected from >200,000 women well in advance of disease (UK Collaborative Trial of Ovarian Cancer Screening) or before and during treatment (SUCCESS Trial).IMPACTAs a result of refined and improved patient stratification, EpiFemCare will:- Reduce the late stage presentation of ovarian & breast cancer by 50%- Reduce the requirement for 50% of breast cancer patients to have adjuvant therapies- Reduce female cancer related fatalities as well as treatment-related morbidity by 20% Ámbito científico natural sciencesbiological sciencesgeneticsDNAmedical and health sciencesclinical medicineoncologybreast cancerengineering and technologyindustrial biotechnologybiomaterialsengineering and technologymedical engineeringmedical laboratory technologylaboratory samples analysisnatural sciencesbiological sciencesgeneticsepigenetics Programa(s) FP7-HEALTH - Specific Programme "Cooperation": Health Tema(s) HEALTH.2012.1.2-1 - Development of technologies with a view to patient group stratification for personalised medicine applications Convocatoria de propuestas FP7-HEALTH-2012-INNOVATION-1 Consulte otros proyectos de esta convocatoria Régimen de financiación CP-FP - Small or medium-scale focused research project Coordinador UNIVERSITY COLLEGE LONDON Aportación de la UE € 2 052 712,00 Dirección GOWER STREET WC1E 6BT LONDON Ver en el mapa Tipo de actividad Higher or Secondary Education Establishments Contacto administrativo Greta Borg-Carbott (Ms.) Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Coste total Sin datos Participantes (5) Ordenar alfabéticamente Ordenar por aportación de la UE Ampliar todo Contraer todo EUROFINS GENOMICS EUROPE PHARMA AND DIAGNOSTICS PRODUCTS & SERVICES SANGER PCR GMBH Alemania Aportación de la UE € 2 136 106,00 Dirección JAKOB STADLER PLATZ 7 78467 Konstanz Ver en el mapa Región Baden-Württemberg Freiburg Konstanz Tipo de actividad Private for-profit entities (excluding Higher or Secondary Education Establishments) Contacto administrativo Janet Kenklies (Dr.) Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Coste total Sin datos GENEDATA AG Suiza Aportación de la UE € 852 245,00 Dirección MARGARETHENSTRASSE 38 4053 BASEL Ver en el mapa Tipo de actividad Private for-profit entities (excluding Higher or Secondary Education Establishments) Contacto administrativo Timo Wittenberger (Dr.) Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Coste total Sin datos EURAM LIMITED Reino Unido Aportación de la UE € 354 344,00 Dirección LUCY TOWER STREET TOWER HOUSE LN1 1XW Lincoln Ver en el mapa Región East Midlands (England) Lincolnshire Lincolnshire Tipo de actividad Private for-profit entities (excluding Higher or Secondary Education Establishments) Contacto administrativo Andrew Banasik (Mr.) Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Coste total Sin datos LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN Alemania Aportación de la UE € 249 932,00 Dirección GESCHWISTER SCHOLL PLATZ 1 80539 Muenchen Ver en el mapa Región Bayern Oberbayern München, Kreisfreie Stadt Tipo de actividad Higher or Secondary Education Establishments Contacto administrativo Brigitte Rack (Dr.) Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Coste total Sin datos UNIVERZITA KARLOVA Chequia Aportación de la UE € 230 048,00 Dirección OVOCNY TRH 560/5 116 36 Praha 1 Ver en el mapa Región Česko Praha Hlavní město Praha Tipo de actividad Higher or Secondary Education Establishments Contacto administrativo Kristyna Matejkova (Ms.) Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Coste total Sin datos
