Cel Advances in numerical methods and three-dimensional imaging techniques have enabled the quantification of cardiovascular mechanics in subject-specific anatomic and physiologic models. Research efforts have been focused mainly on three areas: pathogenesis of vascular disease, development of medical devices, and virtual surgical planning. However, despite great initial promise, the actual use of patient-specific computer modelling in the clinic has been very limited. Clinical diagnosis still relies entirely on traditional methods based on imaging and invasive measurements and sampling. The same invasive trial-and-error paradigm is often seen in vascular disease research, where animal models are used profusely to quantify simple metrics that could perhaps be evaluated via non-invasive computer modelling techniques. Lastly, medical device manufacturers rely mostly on in-vitro models to investigate the anatomic variations, arterial deformations, and biomechanical forces needed for the design of stents and stent-grafts. In this project, I aim to develop an integrated image-based computer modelling framework for subject-specific cardiovascular simulation with dynamically adapting boundary conditions capable of representing alterations in the physiologic state of the patient. This computer framework will be directly applied in clinical settings to complement and enhance current diagnostic practices, working towards the goal of personalized cardiovascular medicine. Dziedzina nauki medical and health sciencesclinical medicineangiologyvascular diseasesnatural sciencesmathematicsapplied mathematicsnumerical analysis Program(-y) FP7-IDEAS-ERC - Specific programme: "Ideas" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) Temat(-y) ERC-SG-PE8 - ERC Starting Grant - Products and process engineering Zaproszenie do składania wniosków ERC-2012-StG_20111012 Zobacz inne projekty w ramach tego zaproszenia System finansowania ERC-SG - ERC Starting Grant Instytucja przyjmująca KING'S COLLEGE LONDON Wkład UE € 1 491 592,79 Adres STRAND WC2R 2LS London Zjednoczone Królestwo Zobacz na mapie Region London Inner London — West Westminster Rodzaj działalności Higher or Secondary Education Establishments Kontakt administracyjny Paul Labbett (Mr.) Kierownik naukowy Carlos Alberto Figueroa Alvarez (Dr.) Linki Kontakt z organizacją Opens in new window Strona internetowa Opens in new window Koszt całkowity Brak danych Beneficjenci (1) Sortuj alfabetycznie Sortuj według wkładu UE Rozwiń wszystko Zwiń wszystko KING'S COLLEGE LONDON Zjednoczone Królestwo Wkład UE € 1 491 592,79 Adres STRAND WC2R 2LS London Zobacz na mapie Region London Inner London — West Westminster Rodzaj działalności Higher or Secondary Education Establishments Kontakt administracyjny Paul Labbett (Mr.) Kierownik naukowy Carlos Alberto Figueroa Alvarez (Dr.) Linki Kontakt z organizacją Opens in new window Strona internetowa Opens in new window Koszt całkowity Brak danych