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Content archived on 2024-06-18

Development and Application of Super-resolution Localization Microscopy

Objective

"The objective of the present integration proposal is to establish PI’s career potential via the transfer of a state-of-the-art optical microscopy technique called localisation based single molecule detection, at the host institute. This method can enhance the spatial resolution of traditional optical microscopes by an order of magnitude, and can image samples with structures of sub-10 nm. It can be used for the examination of biological (cells, tissues, etc.) and other samples labelled with traditional fluorescent dyes or photoactive proteins. The main objective of system development is to implement polarisation sensitive multicolour imaging in 3D. Furthermore, we aim to minimise the acquisition time, which is currently the key limitation of the method. These developments will make it possible to monitor the dimer, oligomer and fibre formation of proteins. The scientific background established and the equipment procured earlier at the host institute will provide a solid foundation for the implementation of the objectives, however we aim to use the grant for the procurement of additional equipment specifically required for the project. The method proposed in the system will organically supplement the ongoing microscopy research activities at the department with single molecule detection. Wider national and international cooperation would provide the biological background required for applications. The grant would also significantly contribute to the personal career of the applicant, who has been developing similar systems. With the help of the reintegration grant the applicant would transfer the necessary knowledge and know-how to the host institute and the local research community. Based on his existing cooperation the host institute can join the “super-resolution microscopy” research network in Europe. Through his teaching and scientific activities he can contribute to the scientific excellence of Szeged in the narrower context, and that of the EU in a wider one."

Fields of science (EuroSciVoc)

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

FP7-PEOPLE-2013-CIG
See other projects for this call

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

MC-CIG - Support for training and career development of researcher (CIG)

Coordinator

SZEGEDI TUDOMANYEGYETEM
EU contribution
€ 100 000,00
Address
DUGONICS TER 13
6720 Szeged
Hungary

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Region
Alföld és Észak Dél-Alföld Csongrád
Activity type
Higher or Secondary Education Establishments
Links
Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

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