Objetivo Contamination with organic pollutants is widespread in nature and a notorious threat to our water resources. Two central paradigms are currently understood to control biodegradation in groundwater and sediments: (i) Redox gradients and interphases between compartments are hot-spots for contaminant breakdown, and (ii) biodegradation is primarily limited by local electron acceptor availability, in particular of oxygen. My group has published leading contributions to this understanding in recent years, especially in elucidating the ecology of anaerobic toluene degraders in aquifers.This project now aims to question these established paradigms and to elaborate a ground-breaking new perspective of the role of molecular oxygen in pollutant degradation in anoxic compartments. The hypotheses at the heart of the project originate from a combination of own recent findings, partially inconsistent with the current understanding of process and degrader stratification at redox gradients. These are now interpreted in the light of exciting recent advances in the fields of electromicrobiology and oxygenic anaerobic respiration.POLLOX postulates that oxygen-dependent degradation of pollutants in anaerobic compartments is possible by two unrecognised physiological adaptations of degraders. I want to verify the hypothesis that filamentous Desulfobulbaceae can anaerobically oxidise toluene via long-distance (1-2 cm) electron transfer to oxygen across redox gradients (aim 1). Furthermore, I postulate that monooxygenase-dependent toluene degraders, in absence of external oxygen, can be active via self-sustained production of oxygen by nitric oxide dismutation (aim 2). POLLOX proposes to perform targeted lab experiments and field surveys to verify both hypotheses and to elaborate the ecological niches in which respective degraders and processes are relevant in situ (aim 3). The generic mechanisms to be elaborated here have the potential to open new doors for bioremediation in the future. Ámbito científico engineering and technologyenvironmental biotechnologybioremediationnatural sciencesearth and related environmental scienceshydrologynatural sciencesbiological sciencesecology Programa(s) FP7-IDEAS-ERC - Specific programme: "Ideas" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) Tema(s) ERC-CG-2013-LS9 - ERC Consolidator Grant - Applied Life Sciences and Non-Medical Biotechnology Convocatoria de propuestas ERC-2013-CoG Consulte otros proyectos de esta convocatoria Régimen de financiación ERC-CG - ERC Consolidator Grants Institución de acogida UNIVERSITAT BAYREUTH Aportación de la UE € 398 387,00 Dirección UNIVERSITATSSTRASSE 30 95447 Bayreuth Alemania Ver en el mapa Región Bayern Oberfranken Bayreuth, Kreisfreie Stadt Tipo de actividad Higher or Secondary Education Establishments Contacto administrativo Harald Meier (Mr.) Investigador principal Tillmann Joachim Lüders (Dr.) Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Coste total Sin datos Beneficiarios (2) Ordenar alfabéticamente Ordenar por aportación de la UE Ampliar todo Contraer todo UNIVERSITAT BAYREUTH Alemania Aportación de la UE € 398 387,00 Dirección UNIVERSITATSSTRASSE 30 95447 Bayreuth Ver en el mapa Región Bayern Oberfranken Bayreuth, Kreisfreie Stadt Tipo de actividad Higher or Secondary Education Establishments Contacto administrativo Harald Meier (Mr.) Investigador principal Tillmann Joachim Lüders (Dr.) Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Coste total Sin datos HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH Alemania Aportación de la UE € 1 490 533,00 Dirección INGOLSTADTER LANDSTRASSE 1 85764 Neuherberg Ver en el mapa Región Bayern Oberbayern München, Landkreis Tipo de actividad Research Organisations Contacto administrativo Jürgen Ertel (Dr.) Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Coste total Sin datos