Objective
This application is being submitted by Dr Milena De Felice of the University of Arizona (researcher), and Professor Fiona Boissonade of the University of Sheffield (scientist-in-charge and supervisor), who have complementary expertise in different aspects of trigeminal pain. The project will be co-supervised by Dr Aneurin Kennerley, the lead physicist in the University of Sheffield's preclinical MRI facility. The proposed multi-disciplinary project will utilise magnetic resonance imaging (MRI) and immunohistochemical techniques to investigate altered activity in the central nervous system in a novel preclinical model of migraine. The over-arching aims of the project are to further understand the generation of migraine and its symptoms, and to identify the specific brain regions involved. The results of our studies will enable us to correlate MRI changes with the development of migraine-like symptoms and the expression of specific indicators of altered excitability. This will advance our understanding of the mechanisms underlying the development of migraine. We also aim to establish how anti-migraine drugs affect MRI and behavioural responses in our model. This project has the potential to establish a translational MRI model that could be utilised to identify and determine the efficacy of novel therapeutic strategies.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
- natural sciences biological sciences neurobiology
- engineering and technology medical engineering diagnostic imaging magnetic resonance imaging
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-2013-IIF
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
S10 2TN SHEFFIELD
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.