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Content archived on 2024-06-18

High-throughput real-time characterisation of cell-mechanical properties

Objective

We aim to commercialise a new, patent-protected concept to measure mechanical properties of biological cells with flow-cytometer-level throughput and establish its standard application in modern drug development and medical diagnostics. Mechanical properties have recently proven to be a physiologically relevant indicator to determine the state, function and type of biological cells. Analysing mechanical parameters provides a novel method to identify physiological or pathological changes. However, mechanical cell properties are currently not accessible for large-scale applications demanding high-throughput. We developed, designed and realised a hydrodynamic cell stretcher, a microfluidic-based device for analysing mechanical cell properties at rates above 100 cells per second and therefore three orders of magnitude faster than other existing methods. In the proposed project, we want to identify, test and validate the most promising applications of hydrodynamic cell stretching in clinical and pharmaceutical research.

Fields of science (EuroSciVoc)

CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

ERC-2013-PoC
See other projects for this call

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

CSA-SA(POC) - Supporting action (Proof of Concept)

Host institution

TECHNISCHE UNIVERSITAET DRESDEN
EU contribution
€ 149 549,84
Address
HELMHOLTZSTRASSE 10
01069 DRESDEN
Germany

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Region
Sachsen Dresden Dresden, Kreisfreie Stadt
Activity type
Higher or Secondary Education Establishments
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

No data

Beneficiaries (1)

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