High-throughput real-time characterisation of cell-mechanical properties

Project Information

FASTTOUCH

Grant agreement ID: 632222

Project closed

Start date 1 July 2014

End date 31 December 2015

Funded under

• Specific programme: "Ideas" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)

Total cost € 165 775,60

EU contribution € 149 549,84

Coordinated by

TECHNISCHE UNIVERSITAET DRESDEN
Germany

Objective

We aim to commercialise a new, patent-protected concept to measure mechanical properties of biological cells with flow-cytometer-level throughput and establish its standard application in modern drug development and medical diagnostics. Mechanical properties have recently proven to be a physiologically relevant indicator to determine the state, function and type of biological cells. Analysing mechanical parameters provides a novel method to identify physiological or pathological changes. However, mechanical cell properties are currently not accessible for large-scale applications demanding high-throughput. We developed, designed and realised a hydrodynamic cell stretcher, a microfluidic-based device for analysing mechanical cell properties at rates above 100 cells per second and therefore three orders of magnitude faster than other existing methods. In the proposed project, we want to identify, test and validate the most promising applications of hydrodynamic cell stretching in clinical and pharmaceutical research.

Fields of science (EuroSciVoc)

CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.

• medical and health sciences › basic medicine › pharmacology and pharmacy › drug discovery

You need to log in or register to use this function

Programme(s)

• FP7-IDEAS-ERC - Specific programme: "Ideas" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)

Topic(s)

• ERC-OA-2013-PoC - European Research Council ERC Proof of Concept

Call for proposal

ERC-2013-PoC
See other projects for this call

Funding Scheme

CSA-SA(POC) - Supporting action (Proof of Concept)

Host institution

TECHNISCHE UNIVERSITAET DRESDEN

• EU contribution: € 149 549,84
• Address: HELMHOLTZSTRASSE 10 ; 01069 Dresden ; Germany
• Region: Sachsen › Dresden › Dresden, Kreisfreie Stadt
• Activity type: Higher or Secondary Education Establishments
• Total cost: No data

Beneficiaries (1)

TECHNISCHE UNIVERSITAET DRESDEN

Germany

• EU contribution: € 149 549,84
• Address: HELMHOLTZSTRASSE 10 ; 01069 Dresden
• Region: Sachsen › Dresden › Dresden, Kreisfreie Stadt
• Activity type: Higher or Secondary Education Establishments
• Total cost: No data