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AXENIS Humanized Mice – Innovation towards industrial scale-up

Objective

Since 2010, AXENIS has developed proprietary, state-of-the-art humanized mouse models as preclinical tools for biomedical research and biopharmaceutical industry in the field of immunology, infectious diseases, immuno-oncology and inflammation. Humanised mice are extremely attractive and effective to perform a fine evaluation of new therapeutic and diagnostic options in a human-like environment. Overall, humanized mouse preclinical testing benefit to the patients (safer products) and pharmaceutical companies (upfront pre-clinical screening of molecules reducing clinical development costs).
To become a global European leader addressing the health market needs for humanized mouse models, the humanized mouse production activity of the company requires to be scaled up to an industrial level that will better suit the end-users’ expectations. That is a reason why a feasibility study is needed to help AXENIS accessing a comprehensive survey of production scale-up (at least 10-fold) from current ‘low scale level’ (few hundred units per year) to the level of multiple of thousand units per year under optimal regulatory standards; an evaluation of the production costs with the aim of lowering the unit price by at least two; precise valuation of the demand market segments; and a risk assessment of the scale-up project.
The HUMANMICE project is therefore the basis to the future development of the company, to establish humanized mice as a new standard for preclinical studies, develop the next generation of humanized mouse models, create an environment supporting business & collaboration opportunities, minimize the production costs and maximize the corresponding revenues.

Fields of science (EuroSciVoc)

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Programme(s)

Multi-annual funding programmes that define the EU’s priorities for research and innovation.

Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

SME-1 - SME instrument phase 1

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Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

(opens in new window) H2020-SMEInst-2014-2015

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Coordinator

AXENIS
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 50 000,00
Address
PASTEUR BIOTOP 28 RUE DU DOCTEUR ROUX
75015 PARIS
France

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Ile-de-France Ile-de-France Paris
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Links
Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

€ 71 429,00
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