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AXENIS Humanized Mice – Innovation towards industrial scale-up

Objective

Since 2010, AXENIS has developed proprietary, state-of-the-art humanized mouse models as preclinical tools for biomedical research and biopharmaceutical industry in the field of immunology, infectious diseases, immuno-oncology and inflammation. Humanised mice are extremely attractive and effective to perform a fine evaluation of new therapeutic and diagnostic options in a human-like environment. Overall, humanized mouse preclinical testing benefit to the patients (safer products) and pharmaceutical companies (upfront pre-clinical screening of molecules reducing clinical development costs).
To become a global European leader addressing the health market needs for humanized mouse models, the humanized mouse production activity of the company requires to be scaled up to an industrial level that will better suit the end-users’ expectations. That is a reason why a feasibility study is needed to help AXENIS accessing a comprehensive survey of production scale-up (at least 10-fold) from current ‘low scale level’ (few hundred units per year) to the level of multiple of thousand units per year under optimal regulatory standards; an evaluation of the production costs with the aim of lowering the unit price by at least two; precise valuation of the demand market segments; and a risk assessment of the scale-up project.
The HUMANMICE project is therefore the basis to the future development of the company, to establish humanized mice as a new standard for preclinical studies, develop the next generation of humanized mouse models, create an environment supporting business & collaboration opportunities, minimize the production costs and maximize the corresponding revenues.

Field of science

  • /natural sciences/biological sciences/zoology/mammalogy/primatology
  • /medical and health sciences/basic medicine/pharmacology and pharmacy/pharmaceutical drug/vaccines
  • /social sciences/economics and business/economics/production economics
  • /medical and health sciences/medical biotechnology/cells technologies/stem cells
  • /social sciences/economics and business/business and management/business model
  • /natural sciences/biological sciences/cell biology
  • /medical and health sciences/basic medicine/immunology
  • /social sciences/economics and business/business and management/commerce

Call for proposal

H2020-SMEINST-1-2014
See other projects for this call

Funding Scheme

SME-1 - SME instrument phase 1

Coordinator

AXENIS
Address
Pasteur Biotop 28 Rue Du Docteur Roux
75015 Paris
France
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
EU contribution
€ 50 000