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A mathematical platform for Abdominal Aortic Aneurism risk assessment and surgical planning

Objective

Abdominal Aneurysm of the Aorta (AAA) is a degenerative disease of the last segment of the abdominal aorta, representing the 14th leading cause of death for the 60 to 85 year-old age group in US. An estimated 80 million people aged 60 years and older are at risk in Western Europe. To date the most commonly used clinical protocol for surgical acceptance is based on the estimate of AAA diameter. The report prepared for the Agency for Healthcare Research and Quality came to the conclusion that: the annual risk of rupture is 1% or lower for a diameter less than 5.5 cm; the 1-year risk of rupture increases with the aneurysm size; it may exceed 10% in the individuals with diameters above 6 cm.

Assessment of AAA rupture risk has long been a topic of interest in clinical research setting. The ability to estimate patient specific probability of AAA rupture can lead to reduced health care costs, adequate and timely patient diagnostic and comfort.

Math4AAArisk aims at the realization of a mathematical platform to support clinicians through the following steps: (A1) From medical imaging to sizing and morphological characterization of AAA, (A2) Preliminary risk evaluation, (A3) Computer simulation and enhanced risk assessment, (B1) Automatic surgery planner, (C1) Anonymous data base storage.

The proposed mathematical platform yields quantitative physical indicators in real time at the sole request of inputting a few clinical measurements; it is patient adapted, as it integrates with patient’s radiological images, under full control of clinicians; it is aimed at improving the diagnostic analysis and possibly the surgical planning. We wish to establish the viability for a market exploitation of the math4AAArisk platform and identify possible later stage funding opportunities.

Fields of science (EuroSciVoc)

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Programme(s)

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

ERC-POC - Proof of Concept Grant

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Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

(opens in new window) ERC-2015-PoC

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Host institution

ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 51 250,00
Address
BATIMENT CE 3316 STATION 1
1015 LAUSANNE
Switzerland

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Region
Schweiz/Suisse/Svizzera Région lémanique Vaud
Activity type
Higher or Secondary Education Establishments
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

€ 51 250,00

Beneficiaries (3)

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