Obiettivo Hydrogels cross-linked through supramolecular interactions are highly dependant on the dynamic charac- teristics of the physical cross-links. Few fundamental studies have been undertaken to quantitatively de- scribe structure-property relationships for these types of systems. Hydrogels formed from CB[8]-mediated supramolecular physical cross-linking mechanisms have gained significant interest on account of their excel- lent physical and mechanical properties such as self-healing and shear-thinning. This supramolecular motif has been further exploited to introduce and compatibilise a wide variety of different materials into hydrogel networks without phase separation, forming hybrid composite hydrogels attributed with unique and emergent properties. This proposal aims to pioneer the combination of several state-of-the-art characterisation tech- niques into an unique experimental setup (CAM-RIG), which will combine super-resolution and confocal microscopy imaging modalities with simultaneous strain-controlled rheological measurements to investigate fundamental structure-property relationships of these systems. For the first time it will be possible to decon- volute the molecular-level dynamics of the supramolecular physical cross-links from chain entanglement of the polymeric networks and understand their relative contributions on the resultant properties of the hydrogels. Using the fundamental insight gained, a set of key parameters will be determined to maximise the potential of supramolecular biocompatible hydrogels, driving paradigm shifts in sustainable science and biomaterial applications through the precise tuning of physical properties. Campo scientifico natural sciencesphysical sciencesopticsmicroscopysuper resolution microscopynatural sciencesphysical sciencesopticsmicroscopyconfocal microscopyengineering and technologyindustrial biotechnologybiomaterials Parole chiave host-guest chemistry supramolecular hydrogel cucurbituril dynamics Programma(i) H2020-EU.1.1. - EXCELLENT SCIENCE - European Research Council (ERC) Main Programme Argomento(i) ERC-2016-COG - ERC Consolidator Grant Invito a presentare proposte ERC-2016-COG Vedi altri progetti per questo bando Meccanismo di finanziamento ERC-COG - Consolidator Grant Istituzione ospitante THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE Contribution nette de l'UE € 2 038 120,00 Indirizzo TRINITY LANE THE OLD SCHOOLS CB2 1TN Cambridge Regno Unito Mostra sulla mappa Regione East of England East Anglia Cambridgeshire CC Tipo di attività Higher or Secondary Education Establishments Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Partecipazione a programmi di R&I dell'UE Opens in new window Rete di collaborazione HORIZON Opens in new window Costo totale € 2 038 120,00 Beneficiari (1) Classifica in ordine alfabetico Classifica per Contributo netto dell'UE Espandi tutto Riduci tutto THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE Regno Unito Contribution nette de l'UE € 2 038 120,00 Indirizzo TRINITY LANE THE OLD SCHOOLS CB2 1TN Cambridge Mostra sulla mappa Regione East of England East Anglia Cambridgeshire CC Tipo di attività Higher or Secondary Education Establishments Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Partecipazione a programmi di R&I dell'UE Opens in new window Rete di collaborazione HORIZON Opens in new window Costo totale € 2 038 120,00