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Exploitation of dt40 cells to study the mechanism of immunoglobulin gene diversification

Objetivo

We will use the DT40 cell line to investigate the role of immunoglobulin specific transcription factors in targeting of hyper mutation, the mechanism of action of AID in controlling the process and the possible involvement of error prone polymerases.

Tema(s)

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Convocatoria de propuestas

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Coordinador

MEDICAL RESEARCH COUNCIL
Aportación de la UE
Sin datos
Dirección
Hills Road
CB2 2QH CAMBRIDGE
Reino Unido

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Coste total
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