Objective
The project Functionalised Colloidal Capsules (FCC) has two goals:
1) development of a universal methodology for modification of colloidal substrates (polyelectrolyte capsules) with two (several) (bio-) macromolecular functionalities providing control of their ratio and uniform distribution;
2) development of a new approach for manufacturing asymmetrically (north-south) functionalised colloidal particles (polyelectrolyte capsules).
The methodology developed within the 1st goal will result in manufacturing prototypes of biocompatible colloidal drug carriers with increased circulation period and better targeting efficiency for future pharmaceutical applications. One of the functionalities on the surface of a drug carrier will be responsible for hindering non-specific interactions with proteins and cells of the immune system, while the other one will provide recognition of a targeted tissue.
The problem of proper control on the ratio of the two types of the (bio-) macromolecular functionalities will be solved via their preliminary coupling to a common anchoring unit (backbone) resulting in the architecture of (mixed) graft-copolymers. The approach for manufacturing asymmetrically (north-south) functionalised colloidal particles (polyelectrolyte capsules) comprises preliminary protection of one semi-sphere of the particles by reversible adsorption to an oppositely charged polyelectrolyte brush.
The open surface of the partially protected colloidal particles will be modified by adsorption of graft-copolymers synthesized within the 1st goal. The non-modified area on the particles will be modified (if necessary) with another kind of graft-copolymer or linear polyelectrolyte after release of the particles back to the solution.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences physical sciences condensed matter physics soft matter physics
- medical and health sciences basic medicine immunology
- engineering and technology materials engineering coating and films
- natural sciences biological sciences biochemistry biomolecules carbohydrates
- engineering and technology electrical engineering, electronic engineering, information engineering electronic engineering sensors
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2005-MOBILITY-5
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
LONDON
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.