Objective
Cellular Cartilage Instruction has the potential to revolutionize cartilage repair. This phenomenon was recently discovered by CellCoTec (NL, industrial SME) and uses the instructive behaviour of cartilage cells and pliable nature of adult stem cells to eliminate the need for cell culture expansion, enabling a single surgery therapy for cartilage repair. Such a therapy is urgently needed by 1 million patients annually. To exploit the clinical potential of Cellular Cartilage Instruction, the most effective stem cell and cartilage sources have to be identified and a bioreactor based method to reproducibly generate instructive cell-biomaterial implants has to be established. Inter-sectorial and bi-directional transfer of knowledge between CellCoTec and the University of Basel (UBasel, CH, academic) will allow combining complementary expertise in stem cell and chondrocyte sources, as well as in biomaterial and bioreactor development towards the standardized generation of efficiently instructing grafts, within a long-term strategic partnership.
This project has as a core a carefully designed plan for the exchange of researchers (one year exchange periods). A researcher from CellCoTec will acquire knowledge on effective cell sources at UBasel and transfer this back to CellCoTec. A researcher from UBasel will share the expertise in bioreactor systems with CellCoTec, and transfer the know-how on biomaterials and Cellular Cartilage Instruction to UBasel. The benefits of this knowledge transfer on an EU level are substantial. Research activities so far fragmented will be focused and unified into a common collaborative effort of two leading groups toward one goal: to strengthen EU research output in the field of stem cell biology and bioreactors and to generate the basis for commercialisation of Cellular Cartilage Instruction. Accordingly, SME competitiveness will be directly enhanced through investment of EU GDP into this project.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
- engineering and technology environmental biotechnology bioremediation bioreactors
- medical and health sciences clinical medicine surgery
- medical and health sciences medical biotechnology cells technologies stem cells
- engineering and technology industrial biotechnology biomaterials
- medical and health sciences medical biotechnology implants
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2005-MOBILITY-3
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Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
BILTHOVEN
Netherlands
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.