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Content archived on 2024-05-29

Systematic functional analysis of intracellular parasitism as a model of genomes conflict

Objective

The research program is a multidisciplinary functional genomics approach to study fundamental biological processes relevant to human health and to develop bioinformatics tools in systems biology. It will decipher the complex regulatory networks that control basic cellular processes in the context of intracellular pathogen infection as a paradigm of host/pathogen genomes conflict.

This project will model the innate immune response of macrophages from two species (humans and mice) to an intracellular pathogen: Leishmania parasite. This model is one of the most intensively investigated at the levels of parasite, host immune response and genetics, and allows testing and validating theoretical models in the light of already available and expected data. In a combined strategy of experimental and theoretical work, we will systematically capture data on different levels of cellular information using state-of-the-art multiparametric molecular technologies.

Fields of science (EuroSciVoc)

CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

FP6-2005-LIFESCIHEALTH-7
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Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

STREP - Specific Targeted Research Project

Coordinator

BIOBASE GMBH
EU contribution
No data
Total cost

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Participants (8)

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