Objective
The research program is a multidisciplinary functional genomics approach to study fundamental biological processes relevant to human health and to develop bioinformatics tools in systems biology. It will decipher the complex regulatory networks that control basic cellular processes in the context of intracellular pathogen infection as a paradigm of host/pathogen genomes conflict.
This project will model the innate immune response of macrophages from two species (humans and mice) to an intracellular pathogen: Leishmania parasite. This model is one of the most intensively investigated at the levels of parasite, host immune response and genetics, and allows testing and validating theoretical models in the light of already available and expected data. In a combined strategy of experimental and theoretical work, we will systematically capture data on different levels of cellular information using state-of-the-art multiparametric molecular technologies.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques.
- medical and health sciencesbasic medicineimmunology
- natural sciencesbiological sciencesbiological behavioural sciencesethologybiological interactions
- natural sciencesmathematicspure mathematicsmathematical analysisfunctional analysis
- natural sciencesbiological sciencesgeneticsgenomes
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Call for proposal
FP6-2005-LIFESCIHEALTH-7
See other projects for this call
Funding Scheme
STREP - Specific Targeted Research ProjectCoordinator
WOLFENBUTTEL
Germany