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Content archived on 2024-06-18

Infrafrontier The European infrastructure for phenotyping and archiving of model mammalian genomes

Objective

Medically related Life Sciences use the mouse as a model system to understand the molecular basis of health and disease in humans (>95% similarity of genes in humans and mice). An essential task for Biomedical Sciences in the 21st century will be the functional analysis of mouse models for every gene in the mammalian genome. The major bottlenecks identified by the user community will be proper characterization (Mouse Clinics), archiving and dissemination of mouse disease models to the research laboratories. The current capacities, governance structures and funding strategies of existing infrastructures will not be able to serve the upcoming urgent needs. Thus it is imperative to organise and establish now an efficient distributed infrastructure for the phenotyping, archiving and dissemination of mouse models on a well concerted, large-scale and pan-European level. This will be a prerequisite for maintaining Europe’s leading role in the functional annotation of the mouse genome. Infrafrontier will guarantee the accessibility of mouse models and will be essential to facilitate their exploitation. Infrafrontier integrates 15 European laboratories with exceptional track records to implement and run large-scale infrastructures. Infrafrontier builds on existing infrastructures under EMMA and EUMODIC and forms a coalition with a significant number of funding agencies to develop the prerequisites to a common European infrastructure. The Infrafrontier preparatory phase aims to organise a stable and sustainable infrastructure by 1) the identification of the most suitable legal form, 2) developing a business plan based on a sustainable funding concept, 3) reaching a legal agreement between all partners and 4) providing a strategic plan for the construction phase. Infrafrontier will therefore give Europe a leading position in the worldwide competition on resources and knowledge for medically relevant mouse models by providing a user-driven platform.

Fields of science (EuroSciVoc)

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Keywords

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Programme(s)

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Topic(s)

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Call for proposal

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FP7-INFRASTRUCTURES-2007-1
See other projects for this call

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

CP-CSA-Infra - Combination of CP and CSA

Coordinator

HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH
EU contribution
€ 2 534 199,24
Address
INGOLSTADTER LANDSTRASSE 1
85764 Neuherberg
Germany

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Region
Bayern Oberbayern München, Landkreis
Activity type
Research Organisations
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

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Participants (28)

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