Infrafrontier The European infrastructure for phenotyping and archiving of model mammalian genomes

Project Information

INFRAFRONTIER

Grant agreement ID: 211404

Project closed

Start date 1 March 2008

End date 31 December 2012

Funded under

• Specific Programme "Capacities": Research infrastructures

Total cost € 6 091 090,63

EU contribution € 4 500 000,00

Coordinated by

HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH
Germany

Objective

Medically related Life Sciences use the mouse as a model system to understand the molecular basis of health and disease in humans (>95% similarity of genes in humans and mice). An essential task for Biomedical Sciences in the 21st century will be the functional analysis of mouse models for every gene in the mammalian genome. The major bottlenecks identified by the user community will be proper characterization (Mouse Clinics), archiving and dissemination of mouse disease models to the research laboratories. The current capacities, governance structures and funding strategies of existing infrastructures will not be able to serve the upcoming urgent needs. Thus it is imperative to organise and establish now an efficient distributed infrastructure for the phenotyping, archiving and dissemination of mouse models on a well concerted, large-scale and pan-European level. This will be a prerequisite for maintaining Europe’s leading role in the functional annotation of the mouse genome. Infrafrontier will guarantee the accessibility of mouse models and will be essential to facilitate their exploitation. Infrafrontier integrates 15 European laboratories with exceptional track records to implement and run large-scale infrastructures. Infrafrontier builds on existing infrastructures under EMMA and EUMODIC and forms a coalition with a significant number of funding agencies to develop the prerequisites to a common European infrastructure. The Infrafrontier preparatory phase aims to organise a stable and sustainable infrastructure by 1) the identification of the most suitable legal form, 2) developing a business plan based on a sustainable funding concept, 3) reaching a legal agreement between all partners and 4) providing a strategic plan for the construction phase. Infrafrontier will therefore give Europe a leading position in the worldwide competition on resources and knowledge for medically relevant mouse models by providing a user-driven platform.

Fields of science

Not validated

• social sciences › sociology › governance
• natural sciences › mathematics › pure mathematics › mathematical analysis › functional analysis
• natural sciences › biological sciences › genetics › genomes

Keywords

• archiving
• cryopreservation
• mouse clinic
• mouse models of human disease
• mouse repository
• phenotyping

Programme(s)

• FP7-INFRASTRUCTURES - Specific Programme "Capacities": Research infrastructures

Topic(s)

• INFRA-2007-2.2-01 - Preparatory phase for the projects in the 2006 ESFRI Roadmap

Call for proposal

FP7-INFRASTRUCTURES-2007-1
See other projects for this call

Funding Scheme

CP-CSA-Infra - Combination of CP and CSA

Coordinator

HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH

• EU contribution: € 2 534 199,24
• Address: INGOLSTADTER LANDSTRASSE 1 ; 85764 Neuherberg ; Germany
• Region: Bayern › Oberbayern › München, Landkreis
• Activity type: Research Organisations
• Administrative Contact: Jürgen Ertel (Dr.)
• Total cost: No data

Participants (28)

MEDICAL RESEARCH COUNCIL

United Kingdom

• EU contribution: € 464 075,95
• Address: 20 Park Crescent ; W1B 1AL LONDON
• Activity type: Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
• Administrative Contact: Deborah Stephens (Ms.)
• Total cost: No data

CONSIGLIO NAZIONALE DELLE RICERCHE

Italy

• EU contribution: € 333 249,50
• Address: PIAZZALE ALDO MORO 7 ; 00185 Roma
• Region: Centro (IT) › Lazio › Roma
• Activity type: Research Organisations
• Administrative Contact: Glauco Tocchini-Valentini (Prof.)
• Total cost: No data

CENTRE EUROPEEN DE RECHERCHE EN BIOLOGIE ET MEDECINE

France

• EU contribution: € 121 288,10
• Address: Rue Laurent Fries 1 ; 67404 Illkirch Graffenstaden
• Region: Grand Est › Alsace › Bas-Rhin
• Activity type: Research Organisations
• Administrative Contact: Katell Schaeffer (Ms.)
• Total cost: No data

GENOME RESEARCH LIMITED

United Kingdom

• EU contribution: € 71 527,50
• Address: WELLCOME SANGER INSTITUTE WELLCOME GENOME CAMPUS HINXTON ; CB10 1SA SAFFRON WALDEN
• Region: East of England › Essex › West Essex
• Activity type: Research Organisations
• Administrative Contact: David Neil Davison (Mr.)
• Total cost: No data

EREVNITIKO KENTRO VIOIATRIKON EPISTIMON ALEXANDROS FLEMINGK

Greece

• EU contribution: € 125 282,40
• Address: FLEMING STREET 34 ; 16672 Vari-Athens
• Region: Αττική › Aττική › Ανατολική Αττική
• Activity type: Research Organisations
• Administrative Contact: Athina Ikonomidou (Ms.)
• Total cost: No data

KAROLINSKA INSTITUTET

Sweden

• EU contribution: € 78 110,00
• Address: Nobels Vag 5 ; 17177 Stockholm
• Region: Östra Sverige › Stockholm › Stockholms län
• Activity type: Higher or Secondary Education Establishments
• Administrative Contact: Riitta Ljungström (Ms.)
• Total cost: No data

FUNDACAO CALOUSTE GULBENKIAN

Portugal

• EU contribution: € 40 927,50
• Address: AVENIDA BERNA 45A ; 1067-001 LISBOA
• Region: Continente › Área Metropolitana de Lisboa › Área Metropolitana de Lisboa
• Activity type: Research Organisations
• Administrative Contact: José Mário Leite (Dr.)
• Total cost: No data

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS

France

• EU contribution: € 157 557,98
• Address: RUE MICHEL ANGE 3 ; 75794 Paris
• Region: Ile-de-France › Ile-de-France › Paris
• Activity type: Research Organisations
• Administrative Contact: Josette Roger (Ms.)
• Total cost: No data

UNIVERSITAT AUTONOMA DE BARCELONA

Spain

• EU contribution: € 81 563,09
• Address: EDIF A CAMPUS DE LA UAB BELLATERRA CERDANYOLA V ; 08193 Cerdanyola Del Valles
• Region: Este › Cataluña › Barcelona
• Activity type: Higher or Secondary Education Establishments
• Administrative Contact: Katja Schustakowitz (Ms.)
• Total cost: No data

AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS

Spain

• EU contribution: € 78 881,24
• Address: CALLE SERRANO 117 ; 28006 Madrid
• Region: Comunidad de Madrid › Comunidad de Madrid › Madrid
• Activity type: Research Organisations
• Administrative Contact: María Del Mar García (Ms.)
• Total cost: No data

OULUN YLIOPISTO

Finland

• EU contribution: € 70 620,00
• Address: PENTTI KAITERAN KATU 1 ; 90014 Oulu
• Region: Manner-Suomi › Länsi-Suomi › Pohjanmaa
• Activity type: Higher or Secondary Education Establishments
• Administrative Contact: Leila Risteli (Dr.)
• Total cost: No data

EUROPEAN MOLECULAR BIOLOGY LABORATORY

Germany

• EU contribution: € 68 287,50
• Address: Meyerhofstrasse 1 ; 69117 Heidelberg
• Region: Baden-Württemberg › Karlsruhe › Heidelberg, Stadtkreis
• Activity type: Research Organisations
• Administrative Contact: Keith Williamson (Mr.)
• Total cost: No data

HELMHOLTZ-ZENTRUM FUR INFEKTIONSFORSCHUNG GMBH

Germany

• EU contribution: € 178 072,50
• Address: INHOFFENSTRASSE 7 ; 38124 Braunschweig
• Region: Niedersachsen › Braunschweig › Braunschweig, Kreisfreie Stadt
• Activity type: Research Organisations
• Administrative Contact: Michael Strätz (Dr.)
• Total cost: No data

KOBENHAVNS UNIVERSITET

Denmark

• EU contribution: € 64 467,50
• Address: NORREGADE 10 ; 1165 Kobenhavn
• Region: Danmark › Hovedstaden › Byen København
• Activity type: Higher or Secondary Education Establishments
• Administrative Contact: Ivan Kristoffersen (Mr.)
• Total cost: No data

GENIKI GRAMMATIA EREVNAS KAI KAINOTOMIAS

Greece

• EU contribution: No data
• Address: Mesogeion Avenue 14-18 ; 115 10 ATHENS
• Region: Αττική › Aττική › Κεντρικός Τομέας Αθηνών
• Activity type: Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
• Administrative Contact: Aikaterini Galanou (Ms.)
• Total cost: No data

HERMANN VON HELMHOLTZ-GEMEINSCHAFT DEUTSCHER FORSCHUNGSZENTREN EV

Germany

• EU contribution: No data
• Address: AHRSTRASSE 45 ; 53175 BONN
• Region: Nordrhein-Westfalen › Köln › Bonn, Kreisfreie Stadt
• Activity type: Research Organisations
• Administrative Contact: Tania Lieckweg (Dr.)
• Total cost: No data

BUNDESMINISTERIUM FUER BILDUNG UND FORSCHUNG

Germany

• EU contribution: No data
• Address: Heinemannstrasse 2 ; 53175 Bonn
• Region: Nordrhein-Westfalen › Köln › Bonn, Kreisfreie Stadt
• Activity type: Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
• Administrative Contact: Ingrid Zwoch
• Total cost: No data

VETENSKAPSRADET - SWEDISH RESEARCH COUNCIL

Sweden

• EU contribution: € 7 222,50
• Address: BOX 1035 ; 101 38 Stockholm
• Region: Östra Sverige › Stockholm › Stockholms län
• Activity type: Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
• Administrative Contact: Tove Andersson (Dr.)
• Total cost: No data

DEPARTAMENT DE SALUT - GENERALITAT DE CATALUNYA

Spain

• EU contribution: € 7 222,50
• Address: Trav. de les Corts (Pavelló Ave Maria) 131-159 ; 08028 Barcelona
• Region: Este › Cataluña › Barcelona
• Activity type: Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
• Administrative Contact: Ramon Maspons (Dr.)
• Total cost: No data

FUNDACION PARQUE CIENTIFICO DE MADRID-FPCM

Spain

• EU contribution: € 7 222,50
• Address: CALLE FARADAY 7 EDIFICIO CLAID ; 28049 MADRID
• Region: Comunidad de Madrid › Comunidad de Madrid › Madrid
• Activity type: Research Organisations
• Administrative Contact: Ana Martinez (Dr.)
• Total cost: No data

FUNDACION PARA EL CONOCIMIENTO MADRIMASD

Spain

• EU contribution: € 7 222,50
• Address: 6 CALLE DEL MAESTRO ANGEL LLORCA 3 ; 28003 Madrid
• Region: Comunidad de Madrid › Comunidad de Madrid › Madrid
• Activity type: Other
• Administrative Contact: José De La Sota (Mr.)
• Total cost: No data

BIOCEV z.s.p.o.

Czechia

• EU contribution: € 1 500,00
• Address: K vyzkumnym ustavum 1/1083 ; 14220 PRAHA
• Activity type: Research Organisations
• Administrative Contact: Jan Rajnoch (Dr.)
• Total cost: No data

VETERINAERMEDIZINISCHE UNIVERSITAET WIEN

Austria

• EU contribution: € 1 500,00
• Address: Veterinaerplatz 1 ; 1210 Wien
• Region: Ostösterreich › Wien › Wien
• Activity type: Higher or Secondary Education Establishments
• Administrative Contact: Wolfgang Kuenzel (Prof.)
• Total cost: No data

Toronto Centre for Phenogenomics Inc.

Canada

• EU contribution: No data
• Address: Orde Street 25 ; M5T 3H7 Toronto
• Administrative Contact: Michael Gottlieb (Mr.)
• Total cost: No data

MINISTERSTVO SKOLSTVI MLADEZE A TELOVYCHOVY

Czechia

• EU contribution: No data
• Address: Karmelitska 7 ; 11812 PRAGUE
• Activity type: Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
• Administrative Contact: Gabriela Vlckova (Ms.)
• Total cost: No data

INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE

France

• EU contribution: No data
• Address: RUE DE TOLBIAC 101 ; 75654 Paris
• Region: Ile-de-France › Ile-de-France › Paris
• Activity type: Research Organisations
• Administrative Contact: Karine Lanini (Ms.)
• Total cost: No data

MINISTERO DELLA SALUTE

Italy

• EU contribution: No data
• Address: Via Giorgio Ribotta 5 ; 00144 Roma
• Region: Centro (IT) › Lazio › Roma
• Activity type: Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
• Administrative Contact: Massimo Casciello (Dr.)
• Total cost: No data

USTAV MOLEKULARNI GENETIKY AV CR V.V.I.

Czechia

• EU contribution: No data
• Address: VIDENSKA 1083 ; 142 20 Praha 4
• Region: Česko › Praha › Hlavní město Praha
• Activity type: Research Organisations
• Administrative Contact: Radislav Sedlacek (Dr.)
• Total cost: No data