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Content archived on 2024-06-18

United Europeans for the Development of Pharmacogenomics in Multiple Sclerosis

Objective

Multiple sclerosis (MS) is a chronic inflammatory, disabling disease of the central nervous system. Recent studies suggest that over the last 50 years a disproportional increase in incidence of MS in women has taken place. The lifetime costs of MS exceed 1.5 million € per case in the UK, and are likely to be similar in other European countries. There is no definitive cure for MS. Immunomodulatory therapies, such as interferon-β (IFN-β) and glatiramer acetate (GA), are only partially effective. Hence, there is a pressing need both for novel therapeutic targets and for approaches toward increasing the effectiveness of these existing treatments. The focus of the proposed “United Europeans for the development of PHArmacogenomics in MS” (‘UEPHA-MS’) network will be to promote and improve training opportunities in the novel areas of pharmacogenomics, biomarker research and systems biology applied to MS. The main scientific goals of this network are both to improve our knowledge of the mechanisms determining response outcome of existing immunomodulatory therapies and to identify novel therapeutic opportunities. UEPHA-MS is composed of ten internationally recognised research teams from 6 countries with an assortment of expertise in complementary disciplines. UEPHA-MS partners are among Europe’s most pro-active groups in pioneering the novel, supra-disciplinary area of integrated genomics / bioinformatics / systems biology research. The UEPHA-MS network will provide a coherent and internationally competitive platform for training of young scientists based on a series of state-of-the-art lab-based and network-wide activities. UEPHA-MS will boost employment perspectives of young researchers in Europe’s knowledge-based economy by shaping a new generation of scientists with greatly enhanced multidisciplinary aptitudes. This network will be crucial in priming young scientists for Europe’s collective effort toward improved provision of health care based on “personalized medicine”.

Fields of science (EuroSciVoc)

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Keywords

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Call for proposal

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FP7-PEOPLE-2007-1-1-ITN
See other projects for this call

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

MC-ITN - Networks for Initial Training (ITN)

Coordinator

UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA
EU contribution
€ 386 813,00
Address
BARRIO SARRIENA S N
48940 LEIOA
Spain

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Region
Noreste País Vasco Gipuzkoa
Activity type
Higher or Secondary Education Establishments
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Total cost

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No data

Participants (10)

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