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United Europeans for the Development of Pharmacogenomics in Multiple Sclerosis

Objective

Multiple sclerosis (MS) is a chronic inflammatory, disabling disease of the central nervous system. Recent studies suggest that over the last 50 years a disproportional increase in incidence of MS in women has taken place. The lifetime costs of MS exceed 1.5 million € per case in the UK, and are likely to be similar in other European countries. There is no definitive cure for MS. Immunomodulatory therapies, such as interferon-β (IFN-β) and glatiramer acetate (GA), are only partially effective. Hence, there is a pressing need both for novel therapeutic targets and for approaches toward increasing the effectiveness of these existing treatments. The focus of the proposed “United Europeans for the development of PHArmacogenomics in MS” (‘UEPHA-MS’) network will be to promote and improve training opportunities in the novel areas of pharmacogenomics, biomarker research and systems biology applied to MS. The main scientific goals of this network are both to improve our knowledge of the mechanisms determining response outcome of existing immunomodulatory therapies and to identify novel therapeutic opportunities. UEPHA-MS is composed of ten internationally recognised research teams from 6 countries with an assortment of expertise in complementary disciplines. UEPHA-MS partners are among Europe’s most pro-active groups in pioneering the novel, supra-disciplinary area of integrated genomics / bioinformatics / systems biology research. The UEPHA-MS network will provide a coherent and internationally competitive platform for training of young scientists based on a series of state-of-the-art lab-based and network-wide activities. UEPHA-MS will boost employment perspectives of young researchers in Europe’s knowledge-based economy by shaping a new generation of scientists with greatly enhanced multidisciplinary aptitudes. This network will be crucial in priming young scientists for Europe’s collective effort toward improved provision of health care based on “personalized medicine”.

Field of science

  • /social sciences/economics and business/business and management/employment
  • /medical and health sciences/basic medicine/neurology/multiple sclerosis

Call for proposal

FP7-PEOPLE-2007-1-1-ITN
See other projects for this call

Funding Scheme

MC-ITN - Networks for Initial Training (ITN)

Coordinator

UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA
Address
Barrio Sarriena S N
48940 Leioa
Spain
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 386 813
Administrative Contact
Ione Isasa (Ms.)

Participants (10)

FUNDACIO HOSPITAL UNIVERSITARI VALL D'HEBRON - INSTITUT DE RECERCA
Spain
EU contribution
€ 188 522
Address
Passeig Vall D Hebron 119-129 Edificio De Recerca
08035 Barcelona
Activity type
Research Organisations
Administrative Contact
Comabella Manuel (Dr.)
UNIVERSITAETSKLINIKUM HAMBURG-EPPENDORF
Germany
EU contribution
€ 196 758
Address
Martinistrasse 52
20251 Hamburg
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Roland Martin (Prof.)
UNIVERSITAET ROSTOCK
Germany
EU contribution
€ 196 758
Address
Universitatsplatz 1
18055 Rostock
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Elfriede Zeuner
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
France
EU contribution
€ 396 803
Address
Rue De Tolbiac 101
75654 Paris
Activity type
Research Organisations
Administrative Contact
David Brassat (Prof.)
ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM
Netherlands
EU contribution
€ 196 348
Address
Dr Molewaterplein 40
3015 GD Rotterdam
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Rogier Quintus Hintzen (Dr.)
CHARITE - UNIVERSITAETSMEDIZIN BERLIN
Germany
EU contribution
€ 206 658
Address
Chariteplatz 1
10117 Berlin
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Carmen Infante-Duarte (Dr.)
PROGENIKA BIOPHARMA SA
Spain
EU contribution
€ 168 801
Address
Parque Ibaizabal Bidea Edificio 504 Parque Tecnologico Derio
48160 Vizcaya Bizkaia
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Gorka Ramírez
FEDERAL STATE UNITARY ENTERPRISE STATE SCIENTIFIC-RESEARCH INSTITUTE OF GENETICS AND BREEDING OF INDUSTRIAL MICROORGANISMS
Russia
EU contribution
€ 223 117
Address
1St Dorozhny Proezd 1
117545 Moskva
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Alexander Favorov (Dr.)
CONSORCI INSTITUT D'INVESTIGACIONS BIOMEDIQUES AUGUST PI I SUNYER
Spain
EU contribution
€ 198 422
Address
Calle Rossello 149 Puerta Bjs
08036 Barcelona
Activity type
Other
Administrative Contact
Ramon Gomis (Prof.)
UNIVERSIDAD DE NAVARRA

Participation ended

Spain
Address
Campus Universitario Edificio Central
31080 Pamplona
Activity type
Higher or Secondary Education Establishments
Administrative Contact