Objective
Disorders of Sex Development (DSD) constitute a group of rare to very rare mostly heritable disorders affecting the genito-urinary tract and in most instances also the endocrine-reproductive system. We hypothesize that stringent and stepwise analysis of cases with DSD will result in a systematic and reliable discovery of DSD-relevant biochemical, genetic and functional profiles, allowing for the detection of new diagnostic markers, both in steroid biosynthesis as well as in genetics to provide the basis for explaining the nature of these disorders. Characterization of the functional aspects of androgen action as the main basis for sex-related phenotype will improve the understanding of the pathophysiology of DSD phenotypes. This will allow for better decision-making in gender assignment and therapeutic approaches to DSD as well as improve gender medicine in general.
Fields of science
Keywords
Call for proposal
FP7-HEALTH-2007-A
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Funding Scheme
CP-FP - Small or medium-scale focused research projectCoordinator
23562 Lubeck
Germany
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Participants (13)
G12 8QQ Glasgow
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75724 Paris
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CB2 1TN Cambridge
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B15 2TT Birmingham
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3015 GD Rotterdam
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WC1E 6BT LONDON
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56126 Pisa
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17177 Stockholm
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48149 MUENSTER
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69002 Lyon
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80333 Muenchen
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24118 Kiel
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9000 Gent
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