Objective
The development of high resolution, non damaging imaging techniques are crucial for understanding the biological processes occurring at the cellular level. Nonlinear microscopy (NLM) is rapidly establishing as a powerful technique for high resolution imaging of living biological samples. The high peak powers and low pulse energies available from ultrashort pulses, allow an efficient excitation of nonlinear effects with reduced collateral damage when interacting with cells. Ultrashort pulse light has three additional parameters that can be exploited for a more efficient light-cell interaction. i) Pulse shaping, acting on the temporal intensity profile and phase parameters of a pulse will allow for a more efficient and less damaging interaction with the sample. ii) Adaptive optics will be used to modulate the beam’s wavefront spatial distribution parameter. This will allow correcting aberrations for an increased transversal resolution, larger penetration depths and fields of view. As focus spot size is reduced, it will also allow for lower power to be used, preserving living specimens. In this project, we aim, for the first time, to join complementary intersectorial expertise to perform simultaneous pulse shaping and wavefront correction at the sample plane of a NLM. The knowledge of each of the teams will be transferred, based on microscopy applications. Firstly the work will be focused towards implementing adaptive optics to minimise aberrations induced by the setup and by the sample of study. Then pulse shaping will be use to enhance the output signal and reduce side effects (such as photobleaching). Finally, the combined action will result on new contrast generation technique, constituting an important breakthrough in NLM with great implications into bio-medicine.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-2007-3-1-IAPP
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
MC-IAPP - Industry-Academia Partnerships and Pathways (IAPP)
Coordinator
08860 Castelldefels
Spain
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.