Objective The I-DCC coordination and support project responds to the topic defined by HEALTH-2007-2.1.2-6 “International activities in large-scale data gathering and systems biology”. I-DCC integrates European skills, efforts, resources, and infrastructure in an international collaborative programme to establish a European Data Coordination Centre for mouse genetic resources. Large-scale mouse mutagenesis programs have been established worldwide with the aim of creating loss-of-function mutations in all genes in the mouse. At the moment, these resources largely consist of frozen archives of genetically modified mouse embryonic stem cells that can be conveniently disseminated within the international mouse genetics community for the purpose of generating knockout mice. Most notably, the EUCOMM, KOMP and NorCOMM projects (based in Europe, the USA and Canada, respectively) have been recently established and are expected to achieve near-complete coverage of all mouse genes using high-throughput gene trapping and gene targeting technology. Currently, there is no single point of entry for information on the international ES cell resources. The overall goal of theI-DCC is to lead an effort to establish common data formats and a single portal for access to information on all mutant ES cell resources. This project is built on exceptionally strong international expertise in mouse genome informatics and includes key scientists and bioinformaticians actively involved in the three ongoing large-scale mouse knock out projects (EUCOMM, KOMP and NorCOMM). The I-DCC will 1) coordinate with existing international bioinformatics resources to catalogue and assign unique identifiers to all mouse genes, 2) collaborate with all major ES cell production sites to define standard data formats for the annotation and display of mutant alleles and 3) provide ES cell repositories with standardized data on all ES cell lines and 4) establish a common web portal to facilitate the distribution and use Fields of science medical and health sciencesmedical biotechnologycells technologiesstem cellsnatural sciencesbiological sciencesgeneticsmutationnatural sciencesbiological sciencesgeneticsgenomes Keywords ES cells access achieve bioinformatics common genetic information mouse mutagenesis resources web portal Programme(s) FP7-HEALTH - Specific Programme "Cooperation": Health Topic(s) HEALTH-2007-2.1.2-6 - Coordination and Support Actions in large-scale data gathering and systems biology Call for proposal FP7-HEALTH-2007-B See other projects for this call Funding Scheme CSA-CA - Coordination (or networking) actions Coordinator GENOME RESEARCH LIMITED EU contribution € 803 342,00 Address WELLCOME SANGER INSTITUTE WELLCOME GENOME CAMPUS HINXTON CB10 1SA SAFFRON WALDEN United Kingdom See on map Region East of England East Anglia Cambridgeshire CC Activity type Research Organisations Administrative Contact David Davison (Mr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data Participants (9) Sort alphabetically Sort by EU Contribution Expand all Collapse all HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH Germany EU contribution € 364 167,00 Address INGOLSTADTER LANDSTRASSE 1 85764 Neuherberg See on map Region Bayern Oberbayern München, Landkreis Activity type Research Organisations Administrative Contact Juergen Ertel (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data FONDAZIONE TELETHON ETS Italy EU contribution € 81 086,00 Address VIA VARESE 16/B 00185 Roma See on map Region Centro (IT) Lazio Roma Activity type Research Organisations Administrative Contact Irene Mearelli (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data EUROPEAN MOLECULAR BIOLOGY LABORATORY Germany EU contribution € 301 739,00 Address Meyerhofstrasse 1 69117 Heidelberg See on map Region Baden-Württemberg Karlsruhe Heidelberg, Stadtkreis Activity type Research Organisations Administrative Contact Phil Irving (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data EREVNITIKO KENTRO VIOIATRIKON EPISTIMON ALEXANDROS FLEMINGK Greece EU contribution € 19 260,00 Address FLEMING STREET 34 16672 Vari-Athens See on map Region Αττική Aττική Ανατολική Αττική Activity type Research Organisations Administrative Contact George Kollias (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data THE JACKSON LABORATORY NON PROFIT CORPORATION United States EU contribution € 831 351,00 Address MAIN STREET 610 04609 Bar Harbor See on map Activity type Other Administrative Contact Sven Davisson Links Contact the organisation Opens in new window Website Opens in new window Total cost No data UNIVERSITY OF MANITOBA Canada EU contribution € 120 419,00 Address ADMINISTRATION BUILDING ROOM 202 R3T 2N2 Manitoba See on map Activity type Higher or Secondary Education Establishments Administrative Contact Sabu Mathew (Mr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data MEDICAL RESEARCH COUNCIL Participation ended United Kingdom EU contribution No data Address 20 Park Crescent W1B 1AL LONDON See on map Activity type Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) Administrative Contact Kate Wilson (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data UNIVERSITY COLLEGE LONDON United Kingdom EU contribution € 81 070,00 Address GOWER STREET WC1E 6BT London See on map Region London Inner London — West Camden and City of London Activity type Higher or Secondary Education Establishments Administrative Contact Greta Borg-Carbott (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data THE UNIVERSITY OF EDINBURGH United Kingdom EU contribution € 81 075,00 Address OLD COLLEGE, SOUTH BRIDGE EH8 9YL Edinburgh See on map Region Scotland Eastern Scotland Edinburgh Activity type Higher or Secondary Education Establishments Administrative Contact Valerie Renton (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data