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“The International Data Coordination Centre”

Objective

The I-DCC coordination and support project responds to the topic defined by HEALTH-2007-2.1.2-6 “International activities in large-scale data gathering and systems biology”. I-DCC integrates European skills, efforts, resources, and infrastructure in an international collaborative programme to establish a European Data Coordination Centre for mouse genetic resources. Large-scale mouse mutagenesis programs have been established worldwide with the aim of creating loss-of-function mutations in all genes in the mouse. At the moment, these resources largely consist of frozen archives of genetically modified mouse embryonic stem cells that can be conveniently disseminated within the international mouse genetics community for the purpose of generating knockout mice. Most notably, the EUCOMM, KOMP and NorCOMM projects (based in Europe, the USA and Canada, respectively) have been recently established and are expected to achieve near-complete coverage of all mouse genes using high-throughput gene trapping and gene targeting technology. Currently, there is no single point of entry for information on the international ES cell resources. The overall goal of theI-DCC is to lead an effort to establish common data formats and a single portal for access to information on all mutant ES cell resources. This project is built on exceptionally strong international expertise in mouse genome informatics and includes key scientists and bioinformaticians actively involved in the three ongoing large-scale mouse knock out projects (EUCOMM, KOMP and NorCOMM). The I-DCC will 1) coordinate with existing international bioinformatics resources to catalogue and assign unique identifiers to all mouse genes, 2) collaborate with all major ES cell production sites to define standard data formats for the annotation and display of mutant alleles and 3) provide ES cell repositories with standardized data on all ES cell lines and 4) establish a common web portal to facilitate the distribution and use

Field of science

  • /medical and health sciences/medical biotechnology/cells technologies/stem cells

Call for proposal

FP7-HEALTH-2007-B
See other projects for this call

Funding Scheme

CSA-CA - Coordination (or networking) actions

Coordinator

GENOME RESEARCH LIMITED
Address
The Gibbs Building, Euston Road 215
NW1 2BE London
United Kingdom
Activity type
Research Organisations
EU contribution
€ 803 342
Administrative Contact
David Davison (Mr.)

Participants (9)

HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH
Germany
EU contribution
€ 364 167
Address
Ingolstadter Landstrasse 1
85764 Neuherberg
Activity type
Research Organisations
Administrative Contact
Juergen Ertel (Dr.)
FONDAZIONE TELETHON
Italy
EU contribution
€ 81 086
Address
Via Varese 16/B
00185 Roma
Activity type
Research Organisations
Administrative Contact
Irene Mearelli (Ms.)
EUROPEAN MOLECULAR BIOLOGY LABORATORY
Germany
EU contribution
€ 301 739
Address
Meyerhofstrasse 1
69117 Heidelberg
Activity type
Research Organisations
Administrative Contact
Phil Irving (Dr.)
BIOMEDICAL SCIENCES RESEARCH CENTER ALEXANDER FLEMING
Greece
EU contribution
€ 19 260
Address
Fleming Street 34
16672 Vari-athens
Activity type
Research Organisations
Administrative Contact
George Kollias (Dr.)
THE JACKSON LABORATORY NON PROFIT CORPORATION
United States
EU contribution
€ 831 351
Address
Main Street 610
04609 Bar Harbor
Activity type
Other
Administrative Contact
Sven Davisson
UNIVERSITY OF MANITOBA
Canada
EU contribution
€ 120 419
Address
Administration Building Room 202
R3T 2N2 Manitoba
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Sabu Mathew (Mr.)
MEDICAL RESEARCH COUNCIL

Participation ended

United Kingdom
Address
North Star Avenue Polaris House 2 Floor David Phillips Building
SN2 1FL Swindon
Activity type
Research Organisations
Administrative Contact
Kate Wilson (Dr.)
University College London
United Kingdom
EU contribution
€ 81 070
Address
Gower Street
WC1E 6BT London
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Greta Borg-Carbott (Ms.)
THE UNIVERSITY OF EDINBURGH
United Kingdom
EU contribution
€ 81 075
Address
Old College, South Bridge
EH8 9YL Edinburgh
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Valerie Renton (Ms.)