Objective There is an urgent need to better understand the basic biology of Clostridium as a prerequisite for both countering the diseases they cause (C.difficile C.perfringens and C.botulinum) and exploiting their beneficial properties in industry (biofuels by C.acetobutylicum) and medicine (cancer therapy by C.sporogenes). Attainment of this goal is being impeded because: (i) European research efforts are fragmented; (ii) there is no coherence between researchers working on pathogenic species and industrially important strains; (iii) there is a demonstrable (SCF-CT-2005-029958) lack of trained young clostridial researchers; (iv) there is inadequate networking between industry and academia, and; (v) effective exploitation of the amassed clostridial genome data has been precluded by a woeful inadequacy in procedures for gene inactivation. Removal of these impediments cannot be achieved at a national level, but requires the creation of a transnational network of multi-disciplinary experts,active in different scientific sectors. The technical hurdle to progress has now been solved by partner 1, who has developed a highly effective andreproducible gene knock-out system. The remaining hurdles will be overcome by bringing together a multidisciplinary team of research expertise from 7 different EU states drawn from Academia (5), Government (3) and different sectors of Industry (3). A principal focus will be to address the deficiency in critical mass by providing young researchers with world class, state-of-the-art, multidisciplinary training in leading scientific and biotechnological skills that have relevance to medical countermeasures against pathogens and the exploitation of non-pathogens in industrial processes and disease intervention. These measures will establish Europe as a ‘Centre of Excellence’ for clostridial research, propelling the community to the forefront of the field, eclipsing the efforts of the rest of the world, and in particular the USA and Japan. Fields of science medical and health sciencesclinical medicineoncologynatural sciencesbiological sciencesgeneticsgenomesengineering and technologyindustrial biotechnologybiomaterialsbiofuels Keywords Anticancer therapy Biofuels Biotechnology Diagnostics Infections Microbiology Programme(s) FP7-PEOPLE - Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) Topic(s) FP7-PEOPLE-ITN-2008 - Marie Curie Action: "Networks for Initial Training" Call for proposal FP7-PEOPLE-ITN-2008 See other projects for this call Funding Scheme MC-ITN - Networks for Initial Training (ITN) Coordinator THE UNIVERSITY OF NOTTINGHAM EU contribution € 534 256,80 Address University Park NG7 2RD Nottingham United Kingdom See on map Region East Midlands (England) Derbyshire and Nottinghamshire Nottingham Activity type Higher or Secondary Education Establishments Administrative Contact Paul Cartledge (Mr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data Participants (12) Sort alphabetically Sort by EU Contribution Expand all Collapse all THE UNIVERSITY OF EXETER United Kingdom EU contribution € 444 925,65 Address THE QUEEN'S DRIVE NORTHCOTE HOUSE EX4 4QJ Exeter See on map Region South West (England) Devon Devon CC Activity type Higher or Secondary Education Establishments Administrative Contact Enda Clarke (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data UNIVERSITAET ROSTOCK Germany EU contribution € 428 796,63 Address UNIVERSITATSPLATZ 1 18055 Rostock See on map Region Mecklenburg-Vorpommern Mecklenburg-Vorpommern Rostock, Kreisfreie Stadt Activity type Higher or Secondary Education Establishments Administrative Contact Ursula Kessler (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data TECHNISCHE UNIVERSITAET MUENCHEN Germany EU contribution € 428 796,63 Address Arcisstrasse 21 80333 Muenchen See on map Region Bayern Oberbayern München, Kreisfreie Stadt Activity type Higher or Secondary Education Establishments Administrative Contact Ulrike Ronchetti (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data HELSINGIN YLIOPISTO Finland EU contribution € 453 389,92 Address YLIOPISTONKATU 3 00014 Helsingin Yliopisto See on map Region Manner-Suomi Helsinki-Uusimaa Helsinki-Uusimaa Activity type Higher or Secondary Education Establishments Administrative Contact Katariina Vainio-Mattila (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data ZAVOD ZA ZDRAVSTVENO VARSTVO MARIBOR Slovenia EU contribution € 359 073,43 Address PRVOMAJSKA 1 1 2000 MARIBOR See on map Activity type Research Organisations Administrative Contact Melita Kores (Ms.) Links Contact the organisation Opens in new window Total cost No data ISTITUTO SUPERIORE DI SANITA Italy EU contribution € 428 903,81 Address Viale Regina Elena 299 00161 Roma See on map Region Centro (IT) Lazio Roma Activity type Research Organisations Administrative Contact Rosa Maria Martoccia (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS France EU contribution € 437 562,92 Address RUE MICHEL ANGE 3 75794 Paris See on map Region Ile-de-France Ile-de-France Paris Activity type Research Organisations Administrative Contact Beatrice Saint Cricq (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data METABOLIC EXPLORER SA France EU contribution € 430 416,47 Address BIOPOLE CLERMONT LIMAGNE 63360 Saint Beauzire See on map Region Auvergne-Rhône-Alpes Auvergne Puy-de-Dôme Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Paul Michalet (Mr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data GLAXOSMITHKLINE VACCINES SRL Italy EU contribution € 424 908,42 Address VIA FIORENTINA 1 53100 SIENA See on map Region Centro (IT) Toscana Siena Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Gulli Francesco (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data Phico Therapeutics Ltd Participation ended United Kingdom EU contribution No data Address Babraham Research Campus CB22 3AT Babraham See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Heather Fairhead (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data UNILEVER U.K. CENTRAL RESOURCES LIMITED United Kingdom EU contribution € 440 760,32 Address VICTORIA EMBANKMENT 100 UNILEVER HOUSE EC4Y 0DY LONDON See on map Region London Inner London — West Camden and City of London Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Peter Mcclure (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data INTERVET INTERNATIONAL BV Participation ended Netherlands EU contribution No data Address WIM DE KORVERSTRAAT 35 5831 AN Boxmeer See on map Region Zuid-Nederland Noord-Brabant Noordoost-Noord-Brabant Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Mark Van Heumen (Mr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data
