Objective Since the histopathological diagnosis of tumours is based on microscopy, it would be highly desirable to possess a microscopical technique allowing morphological investigation with a wide zoom range, high resolution and the implementation of multiplex staining. Thus, the goal of the REMEDI project is to explore the possibilites of novel light microscopy techniques, which overcome the diffraction limit of visible light and extend the range of observation to the molecular level of proteins in tumour cells and analyze their interaction and spatial distribution. This proposal aims at the use of single-molecule-microscopy of cancer tissue samples with ultra-high sensitivity, simplified handling and increased speed of analysis. This shall be accomplished by the development of a novel resolution-enhanced microscopy platform with an integrated novel CMOS camera and an adequate image acquistion and analysis software. The REMEDI platform will be validated with two relevant applications: diagnostic/experimental pathology of breast cancer and alterations of plasma membrane components of lymphoma cells. Fields of science natural sciencescomputer and information sciencessoftwareengineering and technologyelectrical engineering, electronic engineering, information engineeringelectronic engineeringsensorsoptical sensorsnatural sciencesbiological sciencesbiochemistrybiomoleculesproteinsnatural sciencesphysical sciencesopticsmicroscopymedical and health sciencesclinical medicineoncologybreast cancer Programme(s) FP7-HEALTH - Specific Programme "Cooperation": Health Topic(s) HEALTH-2009-1.2-1 - Development of tools for sensitive and specific in vitro detection of proteins and their interactions for diagnostic, prognostic and monitoring purposes Call for proposal FP7-HEALTH-2009-single-stage See other projects for this call Funding Scheme CP-FP - Small or medium-scale focused research project Coordinator TILL I.D. GMBH EU contribution € 710 000,00 Address Bahnhofstrasse 89 82166 Grafelfing Germany See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Stefanie Graf (Dr.) Links Contact the organisation Opens in new window Total cost No data Participants (4) Sort alphabetically Sort by EU Contribution Expand all Collapse all ANDOR TECHNOLOGY LIMITED United Kingdom EU contribution € 160 400,00 Address Millennium way 7 springvale business park BT12 7AL Belfast See on map Region Northern Ireland Northern Ireland Belfast Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Lynne Cross (Ms.) Links Contact the organisation Opens in new window Total cost No data GEMEINSCHAFTSPRAXIS PROF DR MED AXEL NIENDORF DR MED SYLVIA BROCKMOLLER DR MED ANNEGRET DEBUS GBR Germany EU contribution € 207 000,00 Address Lornsenstrasse 4 22767 Hamburg See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Axel Niendorf (Prof.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data STICHTING RADBOUD UNIVERSITEIT Netherlands EU contribution € 199 600,00 Address Houtlaan 4 6525 XZ Nijmegen See on map Region Oost-Nederland Gelderland Arnhem/Nijmegen Activity type Higher or Secondary Education Establishments Administrative Contact Sandy Devue-Budde (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data TILL PHOTONICS GMBH Germany EU contribution € 303 100,00 Address Lochhamer schlag 21 82166 Grafelfing See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Jan Seele (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data