Objective Multiple sclerosis (MS) is a chronic inflammatory, disabling disease of the central nervous system. Recent studies suggest that over the last 50 years a disproportional increase in incidence of MS in women has taken place. The lifetime costs of MS exceed 1.5 million € per case in the UK, and are likely to be similar in other European countries. There is no definitive cure for MS. Immunomodulatory therapies, such as interferon-β (IFN-β) and glatiramer acetate (GA), are only partially effective. Hence, there is a pressing need both for novel therapeutic targets and for approaches toward increasing the effectiveness of these existing treatments. The focus of the proposed “United Europeans for the development of PHArmacogenomics in MS” (‘UEPHA-MS’) network will be to promote and improve training opportunities in the novel areas of pharmacogenomics, biomarker research and systems biology applied to MS. The main scientific goals of this network are both to improve our knowledge of the mechanisms determining response outcome of existing immunomodulatory therapies and to identify novel therapeutic opportunities. UEPHA-MS is composed of ten internationally recognised research teams from 6 countries with an assortment of expertise in complementary disciplines. UEPHA-MS partners are among Europe’s most pro-active groups in pioneering the novel, supra-disciplinary area of integrated genomics / bioinformatics / systems biology research. The UEPHA-MS network will provide a coherent and internationally competitive platform for training of young scientists based on a series of state-of-the-art lab-based and network-wide activities. UEPHA-MS will boost employment perspectives of young researchers in Europe’s knowledge-based economy by shaping a new generation of scientists with greatly enhanced multidisciplinary aptitudes. This network will be crucial in priming young scientists for Europe’s collective effort toward improved provision of health care based on “personalized medicine”. Fields of science natural sciencesbiological sciencesneurobiologynatural sciencesbiological sciencesgeneticsmedical and health sciencesbasic medicineneurologymultiple sclerosismedical and health scienceshealth sciencespersonalized medicinesocial scienceseconomics and businessbusiness and managementemployment Keywords biomarker multiple sclerosis pharmacogenomics proteomics transcriptomics Programme(s) FP7-PEOPLE - Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) Topic(s) PEOPLE-2007-1-1-ITN - Marie Curie Action: " Networks for Initial Training" Call for proposal FP7-PEOPLE-2007-1-1-ITN See other projects for this call Funding Scheme MC-ITN - Networks for Initial Training (ITN) Coordinator UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA EU contribution € 386 813,00 Address Barrio sarriena s n 48940 Leioa Spain See on map Region Noreste País Vasco Bizkaia Activity type Higher or Secondary Education Establishments Administrative Contact Ione Isasa (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data Participants (10) Sort alphabetically Sort by EU Contribution Expand all Collapse all FUNDACIO HOSPITAL UNIVERSITARI VALL D'HEBRON - INSTITUT DE RECERCA Spain EU contribution € 188 522,00 Address Passeig vall d hebron 119-129 edificio de recerca 08035 Barcelona See on map Region Este Cataluña Barcelona Activity type Research Organisations Administrative Contact Comabella Manuel (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data UNIVERSITAETSKLINIKUM HAMBURG-EPPENDORF Germany EU contribution € 196 758,00 Address Martinistrasse 52 20251 Hamburg See on map Region Hamburg Hamburg Hamburg Activity type Higher or Secondary Education Establishments Administrative Contact Roland Martin (Prof.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data UNIVERSITAET ROSTOCK Germany EU contribution € 196 758,00 Address Universitatsplatz 1 18055 Rostock See on map Region Mecklenburg-Vorpommern Mecklenburg-Vorpommern Rostock, Kreisfreie Stadt Activity type Higher or Secondary Education Establishments Administrative Contact Elfriede Zeuner Links Contact the organisation Opens in new window Website Opens in new window Total cost No data INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE France EU contribution € 396 803,00 Address Rue de tolbiac 101 75654 Paris See on map Region Ile-de-France Ile-de-France Paris Activity type Research Organisations Administrative Contact David Brassat (Prof.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM Netherlands EU contribution € 196 348,00 Address Dr molewaterplein 40 3015 GD Rotterdam See on map Region West-Nederland Zuid-Holland Groot-Rijnmond Activity type Higher or Secondary Education Establishments Administrative Contact Rogier Quintus Hintzen (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data CHARITE - UNIVERSITAETSMEDIZIN BERLIN Germany EU contribution € 206 658,00 Address Chariteplatz 1 10117 Berlin See on map Region Berlin Berlin Berlin Activity type Higher or Secondary Education Establishments Administrative Contact Carmen Infante-Duarte (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data PROGENIKA BIOPHARMA SA Spain EU contribution € 168 801,00 Address Parque ibaizabal bidea edificio 504 parque tecnologico derio 48160 Vizcaya bizkaia See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Gorka Ramírez Links Contact the organisation Opens in new window Website Opens in new window Total cost No data FEDERAL STATE UNITARY ENTERPRISE STATE SCIENTIFIC-RESEARCH INSTITUTE OF GENETICS AND BREEDING OF INDUSTRIAL MICROORGANISMS Russia EU contribution € 223 117,00 Address 1st dorozhny proezd 1 117545 Moskva See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Alexander Favorov (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data CONSORCI INSTITUT D'INVESTIGACIONS BIOMEDIQUES AUGUST PI I SUNYER Spain EU contribution € 198 422,00 Address Calle rossello 149 puerta bjs 08036 Barcelona See on map Region Este Cataluña Barcelona Activity type Other Administrative Contact Ramon Gomis (Prof.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data UNIVERSIDAD DE NAVARRA Participation ended Spain EU contribution No data Address Campus universitario edificio central 31080 Pamplona See on map Region Noreste Comunidad Foral de Navarra Navarra Activity type Higher or Secondary Education Establishments Administrative Contact Links Contact the organisation Opens in new window Website Opens in new window Total cost No data