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Identification of relevant diagnostic antigens for bovine tuberculosis: influences of animal and regional disease patterns

Objective

A high incidence of bovine tuberculosis is a major impediment to the agricultural economies of many developing countries, including Latin America. This disease, which persists at lower incidences in Europe, can infect man and is a serious threat especially where AIDS is prevalent. Current methods to eradicate bovine tuberculosis use skin tests with crude antigens which lack specificity and cannot differentiate non-symptomatic cases from those with severe diseases (which spread infection). The present project will identify new antigens for use in better tests with defined applications as required in regions of different disease incidence. The tests will be optimised for field situations in Latin America (high incidence)and Europe (low incidence). Ultimately, antigens which are recognised by cattle with different levels of disease will be identified for use in efficient disease control programmes.

Topic(s)

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Call for proposal

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Coordinator

THE QUEEN'S UNIVERSITY OF BELFAST
Address
Stoney Road , Stormont
BT4 3SD Belfast
United Kingdom

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Participants (3)

NATIONAL INSTITUTE OF AGRICULTURAL RESEARCH
Argentina
Address
Los Reseros Y Las Cabanias
1708 Moron

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STATENS SERUM INSTITUT
Denmark
Address
5,Artillerivej 5
2300 Koepenhagen

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UNIVERSIDAD NACIONAL AUTONOMA DE MEXICO
Mexico
Address

04510 Mexico D.f.

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