An international collaborative study of icsi:child and family outcomes (ICSI-CFO)

Objective

Aim: to investigate the implications for family health and the health of children conceived after Intracytoplasmic Sperm Injection (ICSI), a new technology in the treatment of infertility, which is now used in over 750, assisted reproductive clinics in Europe. ICSI conceived children are expected to display the following in comparison with naturally and regular in-vitro-fertilisation conceived children; a greater occurrence of minor physical anomalies, a greater rate of fine/gross motor difficulties and temperamental or behavioural problems. Design: a minimum of 650 British, Belgian, Greek, Swedish, and Danish children born following ICSI will be assessed for cognitive function, psycho-motor co-ordination, behaviour and physical health at age 5 years. Singleton children will be compared with two control populations, matched for socio-demographic factors; one of 500 normally conceived children, and the other 500 conventional IVF conceived children

Programme(s)

• FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002

Topic(s)

• 1.1.1.-10. - Public health and health services research

Funding Scheme

CSC - Cost-sharing contracts

Coordinator

Birkbeck College, University of London

Address

Malet Street, Bloomsbury
WC1E 7HX London
United Kingdom

Participants (4)

ARISTOTLE UNIVERSITY OF THESSALONIKI

Greece

Address

University Campus, Egnatia Street, Administration
54006 Thessaloniki

COPENHAGEN UNIVERSITY HOSPITAL

Denmark

Address

Blegdamsvej 9
2100 Koepenhagen

GOETEBORG UNIVERSITY

Sweden

Address

Sahlgrenska Sjukhuset
413 45 Göteborg

VRIJE UNIVERSITEIT BRUSSEL

Belgium

Address

Pleinlaan 2
1050 Bruxelles