Objective
Breast cancer is currently the most prevalent form of cancer affecting women all around the world. The treatment of early stage breast carcinoma involves either lumpectomy followed by radiotherapy or mastectomy. In the former case, only the tumour is removed but asymmetry and distortion of patient's breast may occur. To date, there are no tools that can accurately predict the cosmetic outcome of lumpectomy or breast augmentation surgery, which is to a large extent dependent upon the surgeon's experience and subjective judgement and, therefore, the result of such intervention procedures cannot be fully guaranteed. Thus, there is an acute need for a pre-surgical methodology that could provide both valuable information to the surgical team on pre-operative planning and guarantee a successful cosmetic outcome for the patient.
The present proposal aims to develop an efficient and accurate numerical tool for realistically simulating oncoplastic breast surgery. The proposed numerical procedure will be based on the newly established Isogeometric Analysis methodology, in order to simulate the mechanical behavior of breast tissues that undergo large deformations during the incision, excision and wound healing process of standard lumpectomy surgery, as well as in breast augmentation with prosthetic implants. To this end, the proposed numerical procedure will be capable of incorporating patient-specific breast geometries obtained, in the initial development phase, through magnetic resonance imaging. As a result, it is expected that the proposed computational framework could assist surgeons in breast surgery pre-operative planning, while providing them with a valuable tool for the cosmetic outcome assessment.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
- medical and health sciences clinical medicine surgery
- medical and health sciences clinical medicine oncology breast cancer
- medical and health sciences medical biotechnology implants breast implants
- engineering and technology medical engineering diagnostic imaging magnetic resonance imaging
- natural sciences mathematics applied mathematics numerical analysis
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-2013-IEF
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Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
WC1E 6BT LONDON
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.