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Diabetes Reversing Implants with enhanced Viability and long-term Efficacy

Deliverables

Outcomes of patients and citizens panel’s report

In order to link DRIVE to society through science-society dialogues on chances, risks and ethical aspects of DRIVE, patient and citizen panels will be organised in the framework of WP8. In order to overcome the classical one-way communication with scientists in the role of experts providing information and public in the role of lay-people receiving information, engaging in a two-way dialogue at eye level between scientists and patients/public is DRIVE’s goal.

Report on patient advocacy activities

DRIVE is committed to supporting diabetes patient advocacy groups across the consortiums member countries and indeed across Europe. This task will be managed by NUIG and contributed to by all DRIVE partners who will contact the major diabetes patient advocacy groups in their home countries. The DRIVE consortium will raise the awareness of the importance of diabetes as a problem in modern society through the participation in public events, open lectures and free to attend conferences and support the lobbying of governments by advocacy groups for increased funding towards diabetes research and diabetes services for patients.

Dissemination and Data Management Plan (DMP) and introductory project dissemination material

This task will be initiated by the development of a dissemination and Data Management Plan (DMP), agreed among the partners, that will describe the data to be generated, how they will be recorded, collected, processed, curated, reported and archived and how they will be made accessible for use. INN will have the responsibility to set up this plan which will be approved by the General Assembly.

Project website

A project website will be set up by INN to support the dissemination activities of the project, providing up-to-date information about the project and its results to the public .

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Publications

Advances in polymeric islet cell encapsulation technologies to limit the foreign body response and provide immunoisolation

Author(s): Alan J .Ryan, Hugh S O’Neill, Garry P Duffy, Fergal J O’Brien
Published in: Current Opinion in Pharmacology, Issue 36, 2017, Page(s) 66-71, ISSN 1471-4892
DOI: 10.1016/j.coph.2017.07.013

Tunable injectable alginate-based hydrogel for cell therapy in Type 1 Diabetes Mellitus

Author(s): Albert Espona-Noguera, Jesús Ciriza, Alberto Cañibano-Hernández, Luis Fernandez, Ignacio Ochoa, Laura Saenz del Burgo, Jose Luis Pedraz
Published in: International Journal of Biological Macromolecules, Issue 107, 2018, Page(s) 1261-1269, ISSN 0141-8130
DOI: 10.1016/j.ijbiomac.2017.09.103

Intramuscular islet allotransplantation in type 1 diabetes mellitus.

Author(s): Bertuzzi F, Colussi G, Lauterio A, De Carlis L.
Published in: Eur Rev Med Pharmacol Sci, 2018, ISSN 1128-3602
DOI: 10.26355/eurrev_201803_14588

Effect of Etanercept Concentration on Human Islet Integrity

Author(s): S. Acreman, H. Brandhorst, A. Abraham, P.R.V. Johnson, D. Brandhorst
Published in: Transplantation Proceedings, Issue 49/10, 2017, Page(s) 2327-2329, ISSN 0041-1345
DOI: 10.1016/j.transproceed.2017.11.002

Long-term Effect of Islet Transplantation on Glycemic Variability

Author(s): Federico Bertuzzi, Luciano De Carlis, Mario Marazzi, Antonio Gaetano Rampoldi, Matteo Bonomo, Barbara Antonioli, Marta Cecilia Tosca, Marta Galuzzi, Andrea Lauterio, Danila Fava, Patrizia Dorighet, Andrea De Gasperi, Giacomo Colussi
Published in: Cell Transplantation, Issue 27/5, 2018, Page(s) 840-846, ISSN 0963-6897
DOI: 10.1177/0963689718763751

Non-invasive marker-independent high content analysis of a microphysiological human pancreas-on-a-chip model

Author(s): Aline Zbinden, Julia Marzi, Katharina Schlünder, Christopher Probst, Max Urbanczyk, Scott Black, Eva M. Brauchle, Shannon L. Layland, Udo Kraushaar, Garry Duffy, Katja Schenke-Layland, Peter Loskill
Published in: Matrix Biology, 2019, ISSN 0945-053X
DOI: 10.1016/j.matbio.2019.06.008

Sustained Release of Vascular Endothelial Growth Factor from Poly(ε-caprolactone-PEG-ε-caprolactone)- b -Poly( l -lactide) Multiblock Copolymer Microspheres

Author(s): Karina C. Scheiner, Roel F. Maas-Bakker, Thanh T. Nguyen, Ana M. Duarte, Gert Hendriks, Lídia Sequeira, Garry P. Duffy, Rob Steendam, Wim E. Hennink, Robbert J. Kok
Published in: ACS Omega, Issue 4/7, 2019, Page(s) 11481-11492, ISSN 2470-1343
DOI: 10.1021/acsomega.9b01272