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European Network linking informatics and genomics of helper T cells

Objective

ENLIGHT-TEN is a European Network Linking Informatics and Genomics of Helper T cells: our mission is to provide cross-disciplinary training in cellular immunology and big data analysis such that we train a new generation of researchers to fully exploit the power of emerging technological platforms. Our network of TEN beneficiaries combines T cell expertise with state-of-the-art technologies such as next generation sequencing (NGS), bioinformatics, multi-colour flow cytometry, preclinical models and tailored genome editing. Trainees will acquire a comprehensive knowledge in T cell immunology and the capacity to generate and interrogate big data sets as well as expertise in identifying novel biomarkers and developing therapeutic concepts. As such the training programme will provide an ideal stepping-stone for creative and innovative early stage researchers (ESRs) to enter and strengthen Europe’s academia as well as pharmaceutical and bioinformatics companies.
The research focus of the network lies in the identification of extrinsic and intrinsic factors that control development, differentiation and plasticity of helper T cell subsets with particular emphasis on how T cell differentiation impacts on human diseases. The generation of large data sets is an emerging and challenging field, and there is high demand in both the academic sector as well as pharmaceutical companies for researchers to be able to analyse, integrate and exploit this rich source of information. ENLIGHT-TEN will combine the individual strengths of innovative laboratories and enterprises from complementary disciplines to provide unique interdisciplinary training for 13 ESRs, placing them at the forefront of this emerging field. Trainees will be empowered to perform cutting-edge analysis of the steadily increasing number of different T cell subsets, which play highly diverse and critical roles in the development of autoimmune diseases, making them a key target for pharmaceutical companies.

Coordinator

HELMHOLTZ-ZENTRUM FUR INFEKTIONSFORSCHUNG GMBH
Net EU contribution
€ 498 432,96
Address
Inhoffenstrasse 7
38124 Braunschweig
Germany

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Region
Niedersachsen Braunschweig Braunschweig, Kreisfreie Stadt
Activity type
Research Organisations
Other funding
€ 0,00

Participants (11)

UNIVERSITY COLLEGE LONDON
United Kingdom
Net EU contribution
€ 273 287,88
Address
Gower Street
WC1E 6BT London

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Region
London Inner London — West Camden and City of London
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00
MEDIZINISCHE UNIVERSITAET WIEN
Austria
Net EU contribution
€ 255 934,08
Address
Spitalgasse 23
1090 Wien

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Region
Ostösterreich Wien Wien
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00
Bayer Pharma AG

Participation ended

Germany
Net EU contribution
€ 103 840,20
Address
Muellerstrasse 178
13353 Berlin
Region
Berlin Berlin Berlin
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
EUROPEAN MOLECULAR BIOLOGY LABORATORY

Participation ended

Germany
Net EU contribution
€ 0,00
Address
Meyerhofstrasse 1
69117 Heidelberg
Region
Baden-Württemberg Karlsruhe Heidelberg, Stadtkreis
Activity type
Research Organisations
Other funding
€ 0,00
INSTITUTO DE MEDICINA MOLECULAR JOAO LOBO ANTUNES
Portugal
Net EU contribution
€ 476 712,72
Address
Avenida Prof Egas Moniz
1649 028 Lisboa

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Region
Continente Área Metropolitana de Lisboa Área Metropolitana de Lisboa
Activity type
Research Organisations
Other funding
€ 0,00
THE BABRAHAM INSTITUTE
United Kingdom
Net EU contribution
€ 546 575,76
Address
Babraham Hall
CB22 3AT Cambridge

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Region
East of England East Anglia Cambridgeshire CC
Activity type
Research Organisations
Other funding
€ 0,00
TURUN YLIOPISTO
Finland
Net EU contribution
€ 269 145,36
Address
Yliopistonmaki
20014 Turku

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Region
Manner-Suomi Etelä-Suomi Varsinais-Suomi
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
France
Net EU contribution
€ 262 875,60
Address
Rue De Tolbiac 101
75654 Paris

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Region
Ile-de-France Ile-de-France Paris
Activity type
Research Organisations
Other funding
€ 0,00
QIAGEN AARHUS AS
Denmark
Net EU contribution
€ 249 216,48
Address
Silkeborgvej 2
8000 Aarhus

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Region
Danmark Midtjylland Østjylland
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,12
GENOME RESEARCH LIMITED
United Kingdom
Net EU contribution
€ 273 287,88
Address
The Gibbs Building, Euston Road 215
NW1 2BE London

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Region
London Inner London — West Camden and City of London
Activity type
Research Organisations
Other funding
€ 0,00
BAYER AKTIENGESELLSCHAFT
Germany
Net EU contribution
€ 145 376,28
Address
Kaiser-wilhelm-allee 1
51373 Leverkusen

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Region
Nordrhein-Westfalen Köln Leverkusen, Kreisfreie Stadt
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00

Partners (6)

Partner

Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.

Abcam plc
United Kingdom
Net EU contribution
€ 0,00
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
Partner

Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.

AFFIRIS AG
Austria
Net EU contribution
€ 0,00
Address
Karl Farkas Gasse 22
1030 Wien

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Ostösterreich Wien Wien
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
Partner

Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.

CRISPR Therapeutics Limited
United Kingdom
Net EU contribution
€ 0,00
Address
Stevenage Bioscience Catalyst, Gunnels Wood Road
SG1 2FX Stevenage

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
East of England Bedfordshire and Hertfordshire Hertfordshire
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
Partner

Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.

EAGLE GENOMICS LIMITED
United Kingdom
Net EU contribution
€ 0,00
Address
Biodata Innovation Centre, Wellcome Genome Campus,
CB10 1DR Cambridge

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
East of England East Anglia Cambridgeshire CC
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
Partner

Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.

Genomatix Software GmbH
Germany
Net EU contribution
€ 0,00
Address
Bayerstrasse 85a
80335 Muenchen

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Bayern Oberbayern München, Kreisfreie Stadt
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
Partner

Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.

NOVIMMUNE SA
Switzerland
Net EU contribution
€ 0,00
Address
Chemin Des Aulx 14
1228 Plan Les Ouates Geneve

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Schweiz/Suisse/Svizzera Région lémanique Genève
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00