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Developing multi-modality nanomedicines for targeted annotation of oncogenic signaling pathways

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Publications

Radiochemistry and Preclinical PET Imaging of 68 Ga-Desferrioxamine Radiotracers Targeting Prostate-Specific Membrane Antigen

Author(s): Eleni Gourni, Luigi Del Pozzo, Mark Bartholomä, Yvonne Kiefer, Philipp T. Meyer, Helmut R. Maecke, Jason P. Holland
Published in: Molecular Imaging, Issue 16, 2017, Page(s) 153601211773701, ISSN 1536-0121
DOI: 10.1177/1536012117737010

Chemical aspects of metal ion chelation in the synthesis and application antibody-based radiotracers

Author(s): Eszter Boros, Jason P. Holland
Published in: Journal of Labelled Compounds and Radiopharmaceuticals, 2018, ISSN 0362-4803
DOI: 10.1002/jlcr.3590

Advanced Methods for Radiolabeling Multimodality Nanomedicines for SPECT/MRI and PET/MRI

Author(s): Jennifer Lamb, Jason P. Holland
Published in: Journal of Nuclear Medicine, Issue 59/3, 2018, Page(s) 382-389, ISSN 0161-5505
DOI: 10.2967/jnumed.116.187419

Gallium Complexation, Stability, and Bioconjugation of 1,4,7-Triazacyclononane Derived Chelators with Azaheterocyclic Arms

Author(s): Alexander Schmidtke, Tilman Läppchen, Christian Weinmann, Lorenz Bier-Schorr, Manfred Keller, Yvonne Kiefer, Jason P. Holland, Mark D. Bartholomä
Published in: Inorganic Chemistry, Issue 56/15, 2017, Page(s) 9097-9110, ISSN 0020-1669
DOI: 10.1021/acs.inorgchem.7b01129

Recent applications of a single quadrupole mass spectrometer in 11 C, 18 F and radiometal chemistry

Author(s): Thomas L. Collier, Kenneth Dahl, Nickeisha A. Stephenson, Jason P. Holland, Adam Riley, Steven H. Liang, Neil Vasdev
Published in: Journal of Fluorine Chemistry, Issue 210, 2018, Page(s) 46-55, ISSN 0022-1139
DOI: 10.1016/j.jfluchem.2018.02.009

In vitro and in vivo evaluation of the bifunctional chelator NODIA-Me in combination with a prostate-specific membrane antigen targeting vector

Author(s): Tilman Läppchen, Yvonne Kiefer, Jason P. Holland, Mark D. Bartholomä
Published in: Nuclear Medicine and Biology, Issue 60, 2018, Page(s) 45-54, ISSN 0969-8051
DOI: 10.1016/j.nucmedbio.2018.03.002

Preparation and preclinical evaluation of a 68Ga-labelled c(RGDfK) conjugate comprising the bifunctional chelator NODIA-Me

Author(s): Tilman Läppchen, Jason P. Holland, Yvonne Kiefer, Mark D. Bartholomä
Published in: EJNMMI Radiopharmacy and Chemistry, Issue 3/1, 2018, ISSN 2365-421X
DOI: 10.1186/s41181-018-0043-2

Optimized synthesis and indium complex formation with the bifunctional chelator NODIA-Me

Author(s): Christian Weinmann, Jason P. Holland, Tilman Läppchen, Harald Scherer, Stephan Maus, Tobias Stemler, Hendrik Bohnenberger, Samer Ezziddin, Philipp Kurz, Mark D. Bartholomä
Published in: Organic & Biomolecular Chemistry, Issue 16/40, 2018, Page(s) 7503-7512, ISSN 1477-0520
DOI: 10.1039/c8ob01981a

Photochemische Konjugation und Eintopfradiomarkierung von Antikörpern für Immun-PET

Author(s): Malay Patra, Larissa S. Eichenberger, Gregor Fischer, Jason P. Holland
Published in: Angewandte Chemie, Issue 131/7, 2019, Page(s) 1946-1951, ISSN 0044-8249
DOI: 10.1002/ange.201813287

Frontispiece: Photochemical Conjugation and One-Pot Radiolabelling of Antibodies for Immuno-PET

Author(s): Malay Patra, Larissa S. Eichenberger, Gregor Fischer, Jason P. Holland
Published in: Angewandte Chemie International Edition, Issue 58/7, 2019, ISSN 1433-7851
DOI: 10.1002/anie.201980761

Antibody-based radiopharmaceuticals for imaging and therapy

Author(s): Jason P. Holland
Published in: Journal of Labelled Compounds and Radiopharmaceuticals, Issue 61/9, 2018, Page(s) 610-610, ISSN 0362-4803
DOI: 10.1002/jlcr.3636

Chemical Kinetics of Radiolabelling Reactions

Author(s): Jason P. Holland
Published in: Chemistry - A European Journal, Issue 24/62, 2018, Page(s) 16472-16483, ISSN 0947-6539
DOI: 10.1002/chem.201803261

Photoactive chelates for radiolabelling proteins

Author(s): Larissa S. Eichenberger, Malay Patra, Jason P. Holland
Published in: Chemical Communications, Issue 55/16, 2019, Page(s) 2257-2260, ISSN 1359-7345
DOI: 10.1039/c8cc09660k

Simultaneous Photoradiochemical Labeling of Antibodies for Immuno-Positron Emission Tomography

Author(s): Malay Patra, Simon Klingler, Larissa S. Eichenberger, Jason P. Holland
Published in: iScience, Issue 13, 2019, Page(s) 416-431, ISSN 2589-0042
DOI: 10.1016/j.isci.2019.03.004

The impact of emerging bioconjugation chemistries on radiopharmaceuticals

Author(s): Rachael Fay, Jason P. Holland
Published in: Journal of Nuclear Medicine, Issue 12, 2019, ISSN 0161-5505
DOI: 10.2967/jnumed.118.220806

Photochemical Conjugation and One-Pot Radiolabelling of Antibodies for Immuno-PET

Author(s): Malay Patra, Larissa S. Eichenberger, Gregor Fischer, Jason P. Holland
Published in: Angewandte Chemie International Edition, Issue 58/7, 2019, Page(s) 1928-1933, ISSN 1433-7851
DOI: 10.1002/anie.201813287

Photoradiosynthesis of 68 Ga-Labeled HBED-CC-Azepin-MetMAb for Immuno-PET of c-MET Receptors

Author(s): Rachael Fay, Melanie Gut, Jason P. Holland
Published in: Bioconjugate Chemistry, Issue 30/6, 2019, Page(s) 1814-1820, ISSN 1043-1802
DOI: 10.1021/acs.bioconjchem.9b00342

The Role of Molecular Imaging in Personalised Healthcare

Author(s): JasonP. Holland
Published in: CHIMIA International Journal for Chemistry, Issue 70/11, 2016, Page(s) 787-795, ISSN 0009-4293
DOI: 10.2533/chimia.2016.787